DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and a1cf

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	XP_009304711.1	Gene:	a1cf / 562916	ZFINID:	ZDB-GENE-060824-3	Length:	550	Species:	Danio rerio

Alignment Length:	207	Identity:	48/207 - (23%)
Similarity:	81/207 - (39%)	Gaps:	40/207 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 GSGHTSTSSHSA------NVGVGV---GGGALASGSTGGSGGNSSPDSG-KIYIKNLERSIDNKA 128
            |.|.|.|...:|      ..|..:   .|.....|...|..| |.|:.| :|::..|.|.:....
Zfish     8 GDGLTGTQKEAALRALIQRTGYHIHQENGQRRYGGPPPGWEG-SPPERGSEIFVGKLPRDLFEDE 71

  Fly   129 VYDTFSVFGNILNCNVAKDEDGNSRGYGFVHFDSEEAARAAIEKVNGMLCNNQKV---------- 183
            :......||.|....:..|.:||:|||.||.|.:::.|:.|::::|.....|.::
Zfish    72 LVPLCEKFGKIYEVRMMMDFNGNNRGYAFVTFSTKQEAKNAMKQLNNYEIRNGRLLGVCASVDNC 136

  Fly   184 -HVVKFIPRRDREQEKATHFKNLYVKNLSEEFTEQHLREMFEPYGRITSHKLMLDEEGRSRRFGF 247
             ..|..||:..:.:|.....|.:         |:..|..:..|...         ::.::|.|.|
Zfish   137 RLFVGGIPKTKKREEILAEMKKV---------TDGVLDVIVYPSAA---------DKAKNRGFAF 183

  Fly   248 VAYENPQSALAA 259
            |.||..::|..|
Zfish   184 VEYETHRAAAMA 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	19/80 (24%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	12/58 (21%)
a1cf	XP_009304711.1	hnRNP-R-Q	6..534	CDD:273732	48/207 (23%)
		RRM_SF	55..132	CDD:302621	20/76 (26%)
		RRM_SF	134..218	CDD:302621	16/80 (20%)
		RRM3_ACF	223..305	CDD:240942
		DND1_DSRM	451..529	CDD:291380
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910