DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and u2af2a

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	XP_005157952.1	Gene:	u2af2a / 557103	ZFINID:	ZDB-GENE-050706-131	Length:	470	Species:	Danio rerio

Alignment Length:	214	Identity:	42/214 - (19%)
Similarity:	84/214 - (39%)	Gaps:	53/214 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 GGNSSPDSGKIYIKNLERSIDNKAVYDTFSVF----------GN-ILNCNVAKDEDGNSRGYGFV 158
            |...:..:.::|:.|:...|..:::.|.|:..          || :|...:.:|     :.:.|:
Zfish   134 GSQMTRQARRLYVGNIPFGITEESMMDFFNAQMRLGGLTQAPGNPVLAVQINQD-----KNFAFL 193

  Fly   159 HFDSEEAARAAIEKVNGMLCNNQKVHVVKFIPRRDREQE-------------------------- 197
            .|.|.:....|: ..:|::...|.:.:     ||..:.:
Zfish   194 EFRSVDETTQAM-AFDGIIFQGQSLKI-----RRPHDYQPLPGMSENPSVYVPGSLPVGVVSTVV 252

  Fly   198 -KATHFKNLYVKNLSEEFTEQHLREMFEPYGRITSHKLMLDE-EGRSRRFGFVAYENPQSALAAV 260
             .:.|  .|::..|.....:..::|:...:|.:.:..|:.|. .|.|:.:.|..|.:...:..|:
Zfish   253 PDSAH--KLFIGGLPNYLNDDQVKELLTSFGPLKAFNLVKDSATGLSKGYAFCEYVDVNISDQAI 315

  Fly   261 IGLHGKQLGDNKFLYVARA 279
            .||:|.||||.|.| |.||
Zfish   316 AGLNGMQLGDKKLL-VQRA 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	15/80 (19%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	23/79 (29%)
u2af2a	XP_005157952.1	RRM1_U2AF65	141..222	CDD:240676	16/91 (18%)
		RRM2_U2AF65	257..333	CDD:240677	22/78 (28%)
		RRM3_U2AF65	370..456	CDD:240678
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910