DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and eif3g

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_001016749.1	Gene:	eif3g / 549503	XenbaseID:	XB-GENE-6070198	Length:	310	Species:	Xenopus tropicalis

Alignment Length:	162	Identity:	38/162 - (23%)
Similarity:	65/162 - (40%)	Gaps:	47/162 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   139 ILNCNVAKDEDGNSR----------------GYGFVHFDSEEA-------ARAAIEKVNGMLCNN 180
            |::|.:.|.:...:|                ..|....|.|:|       |:|.:.|..
Frog   143 IVSCRICKGDHWTTRCPYKDTLGPMQKELAEQLGLSTGDKEKAPGAEPEPAQAPVSKTG------ 201

  Fly   181 QKVHVVKFIP--------RRDREQE---KATHFKNLYVKNLSEEFTEQHLREMFEPYGRITSHKL 234
                  |::|        ||....:   :|.....:.|.||||:..|..|:|:|.|:|.|:...|
Frog   202 ------KYVPPSLRDGGSRRGESMQPNRRADDNATIRVTNLSEDTRETDLQELFRPFGSISRIYL 260

  Fly   235 MLDE-EGRSRRFGFVAYENPQSALAAVIGLHG 265
            ..|: .|:|:.|.|:::...:.|..|:.|:.|
Frog   261 AKDKTTGQSKGFAFISFHRREDAARAIAGVSG 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	11/68 (16%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	22/65 (34%)
eif3g	NP_001016749.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..32
		eIF3g	45..164	CDD:372066	4/20 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	179..229		11/61 (18%)
		RRM_eIF3G_like	230..306	CDD:240854	22/63 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910