DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and pabpc4

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_001361458.1	Gene:	pabpc4 / 548470	XenbaseID:	XB-GENE-485185	Length:	626	Species:	Xenopus tropicalis

Alignment Length:	191	Identity:	94/191 - (49%)
Similarity:	136/191 - (71%)	Gaps:	5/191 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 GKIYIKNLERSIDNKAVYDTFSVFGNILNCNVAKDEDGNSRGYGFVHFDSEEAARAAIEKVNGML 177
            |.::||||::||||||:|||||.|||||:|.|..||:| |:||.||||::::||..||||:||||
Frog    99 GNVFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG-SKGYAFVHFETQDAADRAIEKMNGML 162

  Fly   178 CNNQKVHVVKFIPRRDREQE---KATHFKNLYVKNLSEEFTEQHLREMFEPYGRITSHKLMLDEE 239
            .|::||.|.:|..||:||.|   ||..|.|:|:||..|:..::.|:|.|..||:..|.|:|.|..
Frog   163 LNDRKVFVGRFKCRREREAELGAKAKEFTNVYIKNFGEDMDDERLKETFSKYGKTLSVKVMTDPS 227

  Fly   240 GRSRRFGFVAYENPQSALAAVIGLHGKQLGDNKFLYVARALSKAERQQEINRKLEERKRQK 300
            |:|:.||||::|..:.|..||..::||.: :.|.::|.||..|.|||.|:.|:.|:.|:::
Frog   228 GKSKGFGFVSFERHEDANKAVDDMNGKDV-NGKIMFVGRAQKKVERQAELKRRFEQLKQER 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	45/69 (65%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	31/79 (39%)
pabpc4	NP_001361458.1	PABP-1234	11..607	CDD:130689	94/191 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1027234at2759
OrthoFinder	1	1.000	-	-		FOG0000294
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24012
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.110