DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and Rbfox3

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_001034256.1	Gene:	Rbfox3 / 52897	MGIID:	106368	Length:	374	Species:	Mus musculus

Alignment Length:	104	Identity:	31/104 - (29%)
Similarity:	53/104 - (50%)	Gaps:	19/104 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   162 SEEAARAAIEKVNGMLCNNQKVHVVKFIPRRDREQEKATHFKNLYVKNLSEEFTEQHLREMFEPY 226
            ::|||:.          :||::|     |....|:::.   |.|:|.|:...|.:..||:||..:
Mouse    76 ADEAAQT----------DNQQLH-----PSDPTEKQQP---KRLHVSNIPFRFRDPDLRQMFGQF 122

  Fly   227 GRITSHKLMLDEEGRSRRFGFVAYENPQSALAAVIGLHG 265
            |:|...:::.:|.| |:.||||.:|....|..|...|:|
Mouse   123 GKILDVEIIFNERG-SKGFGFVTFETSSDADRAREKLNG 160

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	5/22 (23%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	23/64 (36%)
Rbfox3	NP_001034256.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..105		11/46 (24%)
		ELAV_HUD_SF	<25..170	CDD:273741	31/104 (30%)
		RRM_FOX1_like	99..174	CDD:240853	23/63 (37%)
		Fox-1_C	208..345	CDD:372095
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910