DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and mod

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_001247401.1	Gene:	mod / 43764	FlyBaseID:	FBgn0002780	Length:	542	Species:	Drosophila melanogaster

Alignment Length:	142	Identity:	35/142 - (24%)
Similarity:	64/142 - (45%)	Gaps:	24/142 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 IYIKNL--ERSIDNKAVYDTFSVFGNILNCNVAKDEDGNSRGYGFVHFDSEEAARAAIEKVNGML 177
            :.::|:  ..|..:.|:...|..||::...:|.    .:.....||.|...:||..|:.:::|..
  Fly   342 LVVENVGKHESYSSDALEKIFKKFGDVEEIDVV----CSKAVLAFVTFKQSDAATKALAQLDGKT 402

  Fly   178 CNNQKVHVVKFIPRRDREQEKATHFKNLYVKNLSEEFTEQHLREMFEPYGRITSHKLML------ 236
            .|..:..:.:|        |::|..:.:.|.||:.:.||..||::|...|.|.| .:||
  Fly   403 VNKFEWKLHRF--------ERSTSGRAILVTNLTSDATEADLRKVFNDSGEIES-IIMLGQKAVV 458

  Fly   237 ---DEEGRSRRF 245
               |:||..:.|
  Fly   459 KFKDDEGFCKSF 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	15/71 (21%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	17/53 (32%)
mod	NP_001247401.1	RRM_SF	177..244	CDD:302621
		RRM_SF	260..327	CDD:240668
		RRM_SF	342..411	CDD:240668	15/72 (21%)
		RRM_SF	422..>465	CDD:302621	14/43 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439610
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930