DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and elavl2

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_001002172.2	Gene:	elavl2 / 431719	ZFINID:	ZDB-GENE-040704-9	Length:	389	Species:	Danio rerio

Alignment Length:	199	Identity:	55/199 - (27%)
Similarity:	98/199 - (49%)	Gaps:	17/199 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 LGSGHTSTSSHSANVGVGVGGGALASGSTGG-SGGNSSPDSGKIYIKN-LERSIDNKAVYDTFSV 135
            |.:|.:.|||:..|        ::::..|.. ...|.|.||....|.| |.:::..:.:...|..
Zfish    34 LSNGPSCTSSNGPN--------SVSNTCTSPVEMPNGSEDSKTNLIVNYLPQNMTQEELKSLFGS 90

  Fly   136 FGNILNCNVAKDE-DGNSRGYGFVHFDSEEAARAAIEKVNGMLCNNQKVHVVKFIPRRDREQEKA 199
            .|.|.:|.:.:|: .|.|.|||||::...:.|..||..:||:....:.:.|     ...|....:
Zfish    91 IGEIESCKLVRDKITGQSLGYGFVNYMEPKDAEKAINTLNGLRLQTKTIKV-----SYARPSSAS 150

  Fly   200 THFKNLYVKNLSEEFTEQHLREMFEPYGRITSHKLMLDE-EGRSRRFGFVAYENPQSALAAVIGL 263
            ....||||..|.:..|::.|.::|..:|||.:.::::|: .|.||..||:.::....|..|:.||
Zfish   151 IRDANLYVSGLPKTMTQKELEQLFSQFGRIITSRILVDQVTGVSRGVGFIRFDRRVEAEEAIKGL 215

  Fly   264 HGKQ 267
            :|::
Zfish   216 NGQK 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	20/71 (28%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	22/67 (33%)
elavl2	NP_001002172.2	ELAV_HUD_SF	65..388	CDD:273741	46/160 (29%)
		RRM1_Hu	67..144	CDD:241094	21/81 (26%)
		RRM2_HuB	149..238	CDD:241219	22/71 (31%)
		RRM_SF	303..388	CDD:302621
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910