DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and rbfox1l

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_999940.1	Gene:	rbfox1l / 407613	ZFINID:	ZDB-GENE-040923-2	Length:	382	Species:	Danio rerio

Alignment Length:	174	Identity:	46/174 - (26%)
Similarity:	78/174 - (44%)	Gaps:	26/174 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 PANYHQQQPALNHHTLAAAHHQQQLHHHAAAAGHLSHVGGGHAASNHLAAAAVLGRHGHNSLGSG 76
            |.::....|...:    |.|||.:::.           |..|..:..:.|:     :..:||..
Zfish    71 PLDFSAAHPNSEY----ADHHQLRVYQ-----------GPQHDGTESITAS-----NTDDSLAP- 114

  Fly    77 HTSTSSHSANVGVGVGGGALASGSTGGSGGNSSPDSGKIYIKNLERSIDNKAVYDTFSVFGNILN 141
             .::...|.:|.|..|.|| |.||....||.:.|.  ::::.|:.....:..:...|..||.||:
Zfish   115 -VTSDPQSLSVSVASGSGA-AGGSDEEGGGKAQPK--RLHVSNIPFRFRDPDLRQMFGQFGKILD 175

  Fly   142 CNVAKDEDGNSRGYGFVHFDSEEAARAAIEKVNGMLCNNQKVHV 185
            ..:..:|.| |:|:|||.|:|...|..|.||:||.:...:|:.|
Zfish   176 VEIIFNERG-SKGFGFVTFESAVEADRAREKLNGTIVEGRKIEV 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	22/69 (32%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826
rbfox1l	NP_999940.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	34..79		1/7 (14%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	94..148		17/63 (27%)
		RRM	<143..>237	CDD:223796	24/79 (30%)
		RRM_FOX1_like	147..222	CDD:240853	23/75 (31%)
		Fox-1_C	257..353	CDD:289199
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910