DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and bru3

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_001369050.1	Gene:	bru3 / 39527	FlyBaseID:	FBgn0264001	Length:	552	Species:	Drosophila melanogaster

Alignment Length:	323	Identity:	76/323 - (23%)
Similarity:	119/323 - (36%)	Gaps:	71/323 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 NPANYHQQQPALNHHTLAAAHHQQQLHHHAAAAGHLSHVGGGHAASNHLAAAAVLGRHGHNSLGS 75
            ||..::|..|     ..|.|..|||....||||   :..|...|..|.:||.|....||.|..|.
  Fly   141 NPFVFNQFSP-----YGAYAQQQQQAALMAAAA---TAPGSAAAYMNPMAALATQIPHGLNGTGQ 197

  Fly    76 GHTSTSSHSANVGVGV-------GGGALASGSTGGSGG---NSSPDSGKIYIKNLERSIDNKAVY 130
            ..:..|....|..:|.       ||.|.|:.:...:.|   |..|.:
  Fly   198 PPSLPSPTMPNFNMGANTPNGQPGGAAAAAAAAAAADGVFTNGIPQT------------------ 244

  Fly   131 DTFSVFGNILNCNVAKDEDGNSRGYGFVHFDSEEAARA----------AIEKVNGMLCNNQKVHV 185
               :..|:.|:..:...        |..:.|:.....|          |...|.|.........:
  Fly   245 ---AFPGHPLHLTIPPQ--------GLPNGDAATLQHAFPGLPPFPGVAFPAVYGQFPQALPPPL 298

  Fly   186 VKFIPRRDREQEKATHFK----------NLYVKNLSEEFTEQHLREMFEPYGRITSHKLMLDE-E 239
            ....|   .::|....|.          ||::.:|.:||.:..|.:||.|:|.:.|.|:.:|. .
  Fly   299 AAVAP---TQREDFLMFPGCSISGPEGCNLFIYHLPQEFGDAELMQMFLPFGNVISSKVFIDRAT 360

  Fly   240 GRSRRFGFVAYENPQSALAAVIGLHGKQLGDNKFLYVARALSKAERQQEINRKLEERKRQKAG 302
            .:|:.||||:::||.||.||:..::|.|:|..:.....:....|.|.. .:..|:...:|..|
  Fly   361 NQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDASRPYXQSEFLKRNSQQPTG 423

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	8/79 (10%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	28/90 (31%)
bru3	NP_001369050.1	RRM2_CELF3_4_5_6	40..120	CDD:410043
		ELAV_HUD_SF	43..404	CDD:273741	71/302 (24%)
		RRM3_CELF3_4_5_6	319..397	CDD:241083	27/77 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010