DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and sf3b4

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_989116.1	Gene:	sf3b4 / 394721	XenbaseID:	XB-GENE-492933	Length:	388	Species:	Xenopus tropicalis

Alignment Length:	191	Identity:	60/191 - (31%)
Similarity:	86/191 - (45%)	Gaps:	40/191 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 AAGHLS--------HVGG-----------------GHAASNHLAAAAVLGRHGHNSLGSGHTS-T 80
            |||.:|        :|||                 |...:.|:....|.|:|    .|.|... .
Frog     2 AAGPISERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQH----QGYGFVEFL 62

  Fly    81 SSHSANVGVGVGGGALASGS----TGGSGGNSSPDSG-KIYIKNLERSIDNKAVYDTFSVFGNIL 140
            |...|:..:.:.......|.    ...|..|.:.|.| .|:|.||:..||.|.:|||||.||.||
Frog    63 SEEDADYAIKIMNMIKLYGKPIRVNKASAHNKNLDVGANIFIGNLDPEIDEKLLYDTFSAFGVIL 127

  Fly   141 NC-NVAKDED-GNSRGYGFVHFDSEEAARAAIEKVNGM-LCNNQKVHVVKFIPRRDREQEK 198
            .. .:.:|.| |||:||.|::|.|.:|:.||||.:||. |||  :...|.:..::|.:.|:
Frog   128 QTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCN--RPITVSYAFKKDSKGER 186

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	36/72 (50%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826
sf3b4	NP_989116.1	RRM1_SF3B4	15..88	CDD:240780	13/76 (17%)
sf3b4	NP_989116.1	RRM2_SF3B4	99..181	CDD:240781	38/83 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910