DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and CG4806

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_611955.2	Gene:	CG4806 / 37948	FlyBaseID:	FBgn0260456	Length:	657	Species:	Drosophila melanogaster

Alignment Length:	343	Identity:	75/343 - (21%)
Similarity:	123/343 - (35%)	Gaps:	141/343 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 VGGGALASG-STGGSGGNSSPDSG--------------------KIYIKNL--ERSIDNKAVYDT 132
            ||....:|| .:....|....|||                    |:.|||:  |:.|.|. |.:.
  Fly   166 VGKEDESSGEDSDAESGEDEEDSGESEDEENDEDHKENKDELKSKLDIKNVKREKQISND-VQEG 229

  Fly   133 FSVFGNILNCNV-AKDED----------------------GNSRGYGFVHFDSEEAARAAIE--- 171
            .:||  |.|... |:|.|                      |:|:|..||.|.::|:|...::
  Fly   230 CTVF--IKNVPFDAEDADLRKACRKFGLVSYAIINRQAVSGHSKGTAFVKFKAKESADLCLQAGT 292

  Fly   172 --KV---------------------------------------NGMLCNNQK----VHVVKFIPR 191
              |:                                       .|::....|    |.......|
  Fly   293 EFKLMDEVLDPHPALSREEMKSKQSQENKKDDAKDSRNLYLAREGLIMAGAKAADGVSASDMAKR 357

  Fly   192 RDREQEKATHFKN---------LYVKNLSEEFTEQHLREM------FEPYG-RI-TSHKLMLDE- 238
            .:.||.|....||         |.:.||.:.:..:.|::|      |.|:. |: ..||:..:.
  Fly   358 HELEQVKTQVLKNLNRFVSRNRLSIHNLPQNYDNEKLKQMALTYTGFRPHECRVMREHKVTPEHP 422

  Fly   239 EGRSRRFGFVAYENPQSALAAVIGLHGKQLGDNKFLY-------VA-----RALSK-----AERQ 286
            :|:|:.|||::::..|.||||:     ::|.:|..::       ||     ||:.|     .||.
  Fly   423 QGKSKGFGFLSFDTHQRALAAL-----RKLNNNPNIFGTQSRPIVAFSIEDRAVHKIKEKRTERS 482

  Fly   287 QEIN----RKLEERKRQK 300
            ::.|    .|.:|||.::
  Fly   483 KQNNPTYQNKQQERKERR 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	26/142 (18%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	28/109 (26%)
CG4806	NP_611955.2	RRM	<2..>154	CDD:223796
		RRM_SF	49..124	CDD:302621
		RRM3_RBM28_like	230..306	CDD:240861	16/77 (21%)
		RRM4_RBM28_like	379..468	CDD:240862	24/93 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24012
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100