DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4612 and bru1

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_001260403.1	Gene:	bru1 / 34648	FlyBaseID:	FBgn0000114	Length:	810	Species:	Drosophila melanogaster

Alignment Length:	275	Identity:	61/275 - (22%)
Similarity:	120/275 - (43%)	Gaps:	56/275 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 GRHGHNSLGSGHTST------SSHSANVGVGVGGGALASGSTGGSGGNSS--------------- 109
            |...:|||..|:.::      |:.:|.|.||..|...|:|....:....|
  Fly   273 GTSSNNSLNVGNNNSNPSLGGSNSNALVSVGSNGIMSAAGLVNNNNNPCSANRNVVAMVDDDACF 337

  Fly   110 ----------------PDSGKIYIKNLERSIDNKAVYDTFSVFGNILNCNVAKDE-DGNSRGYGF 157
                            ||:.|:::..:.:|:|...:.:.|..:|.:.:.||.:|: .|.|:|..|
  Fly   338 RLDTDATVTYGEKEPDPDNIKMFVGQVPKSMDESQLREMFEEYGAVHSINVLRDKATGISKGCCF 402

  Fly   158 VHFDSEEAARAAIEKVNGMLCNNQKVHVVKFIPRRDREQEKATHFKNLYVKNLSEEFTEQHLREM 222
            |.|.:..||..|.:.::.:...|...|.::..|.....:.:    :.|:|..|:::..|..:|::
  Fly   403 VTFYTRHAALKAQDALHNVKTLNGMYHPIQMKPADSENRNE----RKLFVGMLNKKLNENDVRKL 463

  Fly   223 FEPYGRITSHKLMLDEEGRSRRFGFVAYENPQSALAAVIGLHGKQLGDNKF-------LYVARAL 280
            ||.:|.|....::.|:.|:|:...||.:....:|::|:    ...|..||.       |.|..|.
  Fly   464 FEVHGAIEECTVLRDQNGQSKGCAFVTFATKHAAISAI----KVTLSQNKIMEGCTSPLVVKFAD 524

  Fly   281 SKAERQQEINRKLEE 295
            ::.|::|   :|:::
  Fly   525 TQKEKEQ---KKIQQ 536

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	17/70 (24%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	22/86 (26%)
bru1	NP_001260403.1	RRM1_CELF1_2_Bruno	356..437	CDD:241075	20/80 (25%)
		ELAV_HUD_SF	359..808	CDD:273741	44/189 (23%)
		RRM2_Bruno_like	443..524	CDD:241080	21/88 (24%)
		RRM3_Bruno_like	722..800	CDD:241084
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010