DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and PABPC1L2A

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_001012995.1	Gene:	PABPC1L2A / 340529	HGNCID:	27989	Length:	200	Species:	Homo sapiens

Alignment Length:	108	Identity:	50/108 - (46%)
Similarity:	72/108 - (66%)	Gaps:	4/108 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 GKIYIKNLERSIDNKAVYDTFSVFGNILNCNVAKDEDGNSRGYGFVHFDSEEAARAAIEKVNGML 177
            |.::||||.::|||||:|:.||.|||||:|.||.||.| .:|||||||..:|:|..||:.:|||.
Human    90 GNVFIKNLGKTIDNKALYNIFSAFGNILSCKVACDEKG-PKGYGFVHFQKQESAERAIDVMNGMF 153

  Fly   178 CNNQKVHVVKFIPRRDREQEK---ATHFKNLYVKNLSEEFTEQ 217
            .|.:|:.|.:|...::||.|:   |....:..||:..|:..|:
Human   154 LNYRKIFVGRFKSHKEREAERGAWARQSTSADVKDFEEDTDEE 196

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	39/69 (57%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	4/16 (25%)
PABPC1L2A	NP_001012995.1	PABP-1234	2..>196	CDD:130689	49/106 (46%)
PABPC1L2A	NP_001012995.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	170..200		8/27 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1027234at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920