DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and Rbp9

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_001259974.1	Gene:	Rbp9 / 33498	FlyBaseID:	FBgn0010263	Length:	684	Species:	Drosophila melanogaster

Alignment Length:	262	Identity:	68/262 - (25%)
Similarity:	117/262 - (44%)	Gaps:	40/262 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 GNPA---NYHQQQPALNHHTLAAAHHQQQLHHHAAAAGHLSHVGGGHAASNHLAAAAVLGRHGHN 71
            |.||   |....|...|..|.|..       ..||.||..::...|.|.:|:.|:        :|
  Fly    32 GGPATANNVTNSQAQTNGGTTATT-------TAAAGAGSTTNAAVGQATANNAAS--------NN 81

  Fly    72 SLGSGHTSTSSHSANVGVGVGGGALASGSTGGSGGNSSPD-SGKIYIKNLERSIDNKAVYDTFSV 135
            :..:.:|:.:::              :.:|..:..|:.|| ...:.:..|.:::....:...|..
  Fly    82 NNNNNNTNNNNN--------------NNATANNNNNNEPDPKTNLIVNYLPQTMSQDEIRSLFVS 132

  Fly   136 FGNILNCNVAKDE-DGNSRGYGFVHFDSEEAARAAIEKVNGMLCNNQKVHVVKFIPRRDREQEKA 199
            ||.:.:|.:.:|: .|.|.|||||::..:|.|..||..:||:...|:.:.|  .|.|...|..|.
  Fly   133 FGEVESCKLIRDKVTGQSLGYGFVNYVKQEDAEKAINALNGLRLQNKTIKV--SIARPSSESIKG 195

  Fly   200 THFKNLYVKNLSEEFTEQHLREMFEPYGRITSHKLMLDE-EGRSRRFGFVAYENPQSALAAVIGL 263
            .   ||||..|.:..|:..|..:|.|||:|.:.:::.|. .|.|:..||:.::....|..|:..|
  Fly   196 A---NLYVSGLPKNMTQSDLESLFSPYGKIITSRILCDNITGLSKGVGFIRFDQRFEADRAIKEL 257

  Fly   264 HG 265
            :|
  Fly   258 NG 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	20/70 (29%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	21/65 (32%)
Rbp9	NP_001259974.1	ELAV_HUD_SF	107..438	CDD:273741	47/158 (30%)
		RRM1_Hu	109..186	CDD:241094	21/78 (27%)
		RRM2_Hu	196..274	CDD:241096	21/67 (31%)
		RRM3_Hu	355..432	CDD:240823
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439616
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840