Protein Alignment CG4612 and HNRNPD

DIOPT Version :9

• Sequence 1: NP_001246493.1
• Gene: CG4612 / 37914
• FlyBaseID: FBgn0035016
• Length: 307
• Species: Drosophila melanogaster
• Sequence 2: NP_112738.1
• Gene: HNRNPD / 3184
• HGNCID: 5036
• Length: 355
• Species: Homo sapiens
• Alignment Length: 300
• Identity: 77/300 - (25%)
• Similarity: 129/300 - (43%)
• Gaps: 67/300 - (22%)

  Fly    33 QQQLHHHAAAAGHLSHVGGGHAASNHLAAAAVLGRHGHNSLGSGHTSTSSHSANVGVGVGGGALA 97
            ::|.....|||...:.|||..........||..|              ::.:|..|.|.|||..:
Human     3 EEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQG--------------AAAAAGSGAGTGGGTAS 53

  Fly    98 SGSTGGSG------------------GNSSP----------DSGKIYIKNLERSIDNKAVYDTFS 134
            .|:.|||.                  .||||          :..|::|..|......|.:.|.||
Human    54 GGTEGGSAESEGAKIDASKNEEDEGHSNSSPRHSEAATAQREEWKMFIGGLSWDTTKKDLKDYFS 118

  Fly   135 VFGNILNCNVAKDE-DGNSRGYGFVHFDSEEAARAAIEKVNGMLCNNQKVHVV--KFI-PRRDRE 195
            .||.:::|.:..|. .|.|||:|||.|...|    :::||     .:||.|.:  |.| |:|.:.
Human   119 KFGEVVDCTLKLDPITGRSRGFGFVLFKESE----SVDKV-----MDQKEHKLNGKVIDPKRAKA 174

  Fly   196 QEKATHFKNLYVKNLSEEFTEQHLREMFEPYGRITSHKLMLDEEGRSRR-FGFVAYENPQSALAA 259
            .:.....|.::|..||.:..|:.:||.|..:|.:.|.:|.:|.:...|| |.|:.::..:..
Human   175 MKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPV--- 236

  Fly   260 VIGLHGKQLGDNKFLYVARALSKAERQQEINRKLEERKRQ 299
                  |::.:.|:..|  .|||.|.:..::::..::::|
Human   237 ------KKIMEKKYHNV--GLSKCEIKVAMSKEQYQQQQQ 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	23/70 (33%)
		RRM3_I_PABPs	202..282	CDD:240826	20/80 (25%)
HNRNPD	NP_112738.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..92		24/102 (24%)
		CBFNT	<60..78	CDD:311868	1/17 (6%)
		RRM1_hnRNPD	99..172	CDD:410150	27/81 (33%)
		RRM2_hnRNPD	183..257	CDD:241027	22/84 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	2	1.870