DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and Rbm45

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_695218.1	Gene:	Rbm45 / 266631	RGDID:	628862	Length:	476	Species:	Rattus norvegicus

Alignment Length:	180	Identity:	51/180 - (28%)
Similarity:	87/180 - (48%)	Gaps:	22/180 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 SGSTGGSGG-------NSSPDSGKIYIKNLERSIDNKAVYDTFSVFGNILNCNVAKDE-DGNSRG 154
            :||:|||||       ...|.:.:|::. :.:......:.:.||.||:|.:..|.:|: ...|:|
  Rat     4 AGSSGGSGGFRPGVDSLDEPPNSRIFLV-ISKYTSESVLREHFSPFGDIQDIWVVRDKHTKESKG 67

  Fly   155 YGFVHFDSEEAARAAIEKVNGMLCNNQKVHVVK-FIPR-------RDREQEKATHFKNLYVKNLS 211
            ..||.|.....|..|:|:::|..........:| ||.:       ||.|.|:.|   .::|. :.
  Rat    68 IAFVKFARSSQACRAMEEMHGQCLGPNDTKPIKVFIAQSRSSGSHRDVEDEELT---RIFVM-IP 128

  Fly   212 EEFTEQHLREMFEPYGRITSHKLMLDE-EGRSRRFGFVAYENPQSALAAV 260
            :.:||:.|||.|:.||.|....::.:: .|.|:..|:|.|..|..|..|:
  Rat   129 KSYTEEDLREKFKVYGDIEYCSVIKNKVTGESKGLGYVRYLKPSQAAQAI 178

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	17/70 (24%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	18/60 (30%)
Rbm45	NP_695218.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20		7/15 (47%)
		RRM1_RBM45	23..104	CDD:240812	20/81 (25%)
		RRM2_RBM45	120..193	CDD:240813	19/63 (30%)
		RRM3_RBM45	248..320	CDD:240814
		RRM4_RBM45	393..460	CDD:240815
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910