DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and gar2

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_593531.1	Gene:	gar2 / 2542869	PomBaseID:	SPAC140.02	Length:	500	Species:	Schizosaccharomyces pombe

Alignment Length:	232	Identity:	58/232 - (25%)
Similarity:	100/232 - (43%)	Gaps:	52/232 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 GSGHTSTSSHSANVGVGVGGGALASGSTGGSGGNSSPDSGK------------------------ 114
            ||..:|:.|.|::......|.  :..|:.....:||.|..|
pombe   200 GSSESSSDSESSSDSSSESGD--SDSSSDSESESSSEDEKKRKAEPASEERPAKITKPSQDSNET 262

  Fly   115 --IYIKNLERSIDNKAVYDTFSVFGNILNCNVAKD-EDGNSRGYGFVHFDSEEAARAAI-----E 171
              :::..|..::|::.:...|..:|.|:...|..| :.|.|:|||:|.|::.|||:||:     :
pombe   263 CTVFVGRLSWNVDDQWLGQEFEEYGTIVGARVIMDGQSGRSKGYGYVDFETPEAAKAAVAANGTK 327

  Fly   172 KVNGMLCNNQKVHVVKFIPR----RDREQEKATHF--------KNLYVKNLSEEFTEQHLREMFE 224
            :::|.:.|....:     ||    :...|::|.:|        ..::|.|||...||..|...|.
pombe   328 EIDGRMVNLDLSN-----PRPANPQPYAQQRAGNFGDQLSEPSDTVFVGNLSFNATEDDLSTAFG 387

  Fly   225 PYGRITSHKLMLD-EEGRSRRFGFVAYENPQSALAAV 260
            ..|.|.|.:|..| :.||.:.||:|.:.:..||...|
pombe   388 GCGDIQSIRLPTDPQSGRLKGFGYVTFSDIDSAKKCV 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	21/75 (28%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	22/68 (32%)
gar2	NP_593531.1	RRM1_gar2	264..339	CDD:240893	21/74 (28%)
gar2	NP_593531.1	RRM2_gar2	368..439	CDD:240894	21/57 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	1	0.960