DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4612 and pabp

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_593377.1	Gene:	pabp / 2541505	PomBaseID:	SPAC57A7.04c	Length:	653	Species:	Schizosaccharomyces pombe

Alignment Length:	193	Identity:	96/193 - (49%)
Similarity:	133/193 - (68%)	Gaps:	6/193 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 SGKIYIKNLERSIDNKAVYDTFSVFGNILNCNVAKDEDGNSRGYGFVHFDSEEAARAAIEKVNGM 176
            :|.::||||:.:|||||::||||.||.||:|.||.||.||::|||||||||.|:|.||||.||||
pombe   167 TGNVFIKNLDPAIDNKALHDTFSAFGKILSCKVAVDELGNAKGYGFVHFDSVESANAAIEHVNGM 231

  Fly   177 LCNNQKVHVVKFIPRRDREQE----KATHFKNLYVKNLSEEFTEQHLREMFEPYGRITSHKLMLD 237
            |.|::||:|...:.||:|:.:    || :|.|:|:|||..|.|||...::|..:|.|||..|:.|
pombe   232 LLNDKKVYVGHHVSRRERQSKVEALKA-NFTNVYIKNLDTEITEQEFSDLFGQFGEITSLSLVKD 295

  Fly   238 EEGRSRRFGFVAYENPQSALAAVIGLHGKQLGDNKFLYVARALSKAERQQEINRKLEERKRQK 300
            :..:.|.||||.|.|.:.|..||..|:.|:....| |||.||..|.||::|:.::.|:.|.:|
pombe   296 QNDKPRGFGFVNYANHECAQKAVDELNDKEYKGKK-LYVGRAQKKHEREEELRKRYEQMKLEK 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	47/69 (68%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	35/79 (44%)
pabp	NP_593377.1	PABP-1234	80..642	CDD:130689	96/193 (50%)
		RRM1_I_PABPs	81..160	CDD:240824
		RRM2_I_PABPs	166..242	CDD:240825	49/74 (66%)
		RRM3_I_PABPs	260..339	CDD:240826	35/79 (44%)
		RRM4_I_PABPs	363..441	CDD:240827
		PolyA	581..644	CDD:197769
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000294
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100425
Panther	1	1.100	-	-	O	PTHR24012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910