DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and bru2

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_001036356.1	Gene:	bru2 / 250811	FlyBaseID:	FBgn0262475	Length:	893	Species:	Drosophila melanogaster

Alignment Length:	321	Identity:	81/321 - (25%)
Similarity:	118/321 - (36%)	Gaps:	95/321 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 NPANYHQQQPALNHHTLAAAHHQQQLHHHAAAAGHLSHVGGGHAASNHLAAAAVLGRHGHNSLGS 75
            :||:|   .|.||.|     |..:...||:.   |...:||..|||...|||..    ..|.||.
  Fly   594 SPAHY---LPGLNFH-----HPPENSAHHSQ---HSPGIGGASAASLSAAAATA----ASNPLGG 643

  Fly    76 GHTSTSSHSANVGVGVGGGALA---------------------------SGSTGGSGGNSSPDSG 113
            ....|.:.:::.|...|.|.||                           |.|:|.:.||||..||
  Fly   644 APPPTPTPTSSAGHAAGAGLLAAPSMSMQNLVALLATPTAHHQLSLHHSSSSSGHNNGNSSATSG 708

  Fly   114 ------------------KIYIKNLERSIDNKAV------YDTFSVFGNILNCNVAKDEDG---- 150
                              ..|  |:.:.|.:.|.      ......|..:...|.|.....
  Fly   709 LHNQRLTYAAAPPPPPISTTY--NMPQLIGHTATPTQPGGSSQSLTFNALWPPNAADPYSSSLSG 771

  Fly   151 --NSRGYGFVHFD-SEEAARAAIEKVNGMLCNNQKVHVVKFIPRRDREQEKATHFKNLYVKNLSE 212
              |...||..... :..|.:||...|.|                   :|.:.....||::.:|.:
  Fly   772 LTNGAAYGAASQPVTTSALQAAAAGVTG-------------------KQIEGPDGSNLFIYHLPQ 817

  Fly   213 EFTEQHLREMFEPYGRITSHKLMLDEE-GRSRRFGFVAYENPQSALAAVIGLHGKQLGDNK 272
            ||.:..|...|.|:|.:.|.|:.:|:: ..|:.||||:|:||.||.||:..:||.|:|..:
  Fly   818 EFIDTDLASTFLPFGNVLSAKVFIDKQTNLSKCFGFVSYDNPHSANAAIQAMHGFQIGSKR 878

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	15/82 (18%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	28/72 (39%)
bru2	NP_001036356.1	RRM1_CELF1_2_Bruno	294..375	CDD:241075
		RRM2_Bruno_like	381..461	CDD:241080
		RRM_SF	801..892	CDD:302621	29/78 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010