DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4612 and ELAVL1

DIOPT Version :9

Sequence 1:NP_001246493.1 Gene:CG4612 / 37914 FlyBaseID:FBgn0035016 Length:307 Species:Drosophila melanogaster
Sequence 2:NP_001410.2 Gene:ELAVL1 / 1994 HGNCID:3312 Length:326 Species:Homo sapiens


Alignment Length:279 Identity:73/279 - (26%)
Similarity:108/279 - (38%) Gaps:72/279 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    69 GHNSLGSGHTS--TSSHSANVGVGVGGGALASGSTGGSGGNSSPD---SGKIYIKNLERSIDNKA 128
            || |||.|..:  |:..:......:.|..|.|.:...|....|.:   ...:||..|.|::..|.
Human    58 GH-SLGYGFVNYVTAKDAERAINTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKD 121

  Fly   129 VYDTFSVFGNILNCNVAKDE-DGNSRGYGFVHFDSEEAARAAIEKVNGMLCNNQKVH-------- 184
            |.|.||.||.|:|..|..|: .|.|||..|:.||....|..||...||        |        
Human   122 VEDMFSRFGRIINSRVLVDQTTGLSRGVAFIRFDKRSEAEEAITSFNG--------HKPPGSSEP 178

  Fly   185 -VVKFIPRRDREQEKA-------------------------------THFKNL------------ 205
             .|||....::.:..|                               .|...|            
Human   179 ITVKFAANPNQNKNVALLSQLYHSPARRFGGPVHHQAQRFRFSPMGVDHMSGLSGVNVPGNASSG 243

  Fly   206 ---YVKNLSEEFTEQHLREMFEPYGRITSHKLMLD-EEGRSRRFGFVAYENPQSALAAVIGLHGK 266
               ::.||.::..|..|.:||.|:|.:|:.|::.| ...:.:.||||...|.:.|..|:..|:|.
Human   244 WCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGY 308

  Fly   267 QLGDNKFLYVARALSKAER 285
            :||| |.|.|:...:|:.:
Human   309 RLGD-KILQVSFKTNKSHK 326

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4612NP_001246493.1 RRM2_I_PABPs 115..185 CDD:240825 28/79 (35%)
RRM3_I_PABPs 202..282 CDD:240826 27/95 (28%)
ELAVL1NP_001410.2 ELAV_HUD_SF 19..326 CDD:273741 73/277 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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