DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and sart-3

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_502136.1	Gene:	sart-3 / 178053	WormBaseID:	WBGene00007111	Length:	836	Species:	Caenorhabditis elegans

Alignment Length:	237	Identity:	50/237 - (21%)
Similarity:	93/237 - (39%)	Gaps:	59/237 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 ALASGSTGGSGGNSSPDSGKIYIKNLERSIDNKAVYDTFSVFGNILNCNVAKDE----------- 148
            |.:|.:...|..:|:|..|...::......:     |..::|.:.|:....:||
Worm   560 AKSSSAVSSSNASSTPAPGSFAVQKAAPGTE-----DARTIFVSNLDFTTTEDEIRQAIEGVASI 619

  Fly   149 ----DGNS----RGYGFVHFDSEEAARAAIEKVNGMLCNNQKVHV---VKFIPRRDREQEKATHF 202
                ..||    ||:.:|..::::.|:.|:.|        .:|.|   ..||...|  .||...|
Worm   620 RFARKANSDLVHRGFAYVVMENDQKAQQALLK--------DRVPVKGRPMFISAND--PEKRVGF 674

  Fly   203 K--------NLYVKNLSEEFTEQHLREMFEPYGRITSHKLMLDEEGRSRRFGFVAYENPQSALAA 259
            |        .::|:|:..:.|:..|:.:|..:|.:||.:.:..::|:.:...||.::...||...
Worm   675 KFSTTLEKSKVFVRNVHFQATDDELKALFSKFGTVTSVRRVTHKDGKPKGIAFVDFDTEASAQKC 739

  Fly   260 VIGLHGKQLGDNKFLYVARALSKAERQQEINRKLEERKRQKA 301
            |..      ||...|        .||:.|:.......|:.|:
Worm   740 VAS------GDKLML--------RERELEVALSNPPVKKDKS 767

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	14/88 (16%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	19/87 (22%)
sart-3	NP_502136.1	RRM_SF	681..761	CDD:418427	20/93 (22%)
		Lsm_interact	818..835	CDD:398843
		TPR	209..494	CDD:223533
		RRM_SF	594..664	CDD:418427	15/77 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.861654	Normalized mean entropy	S4474
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950