DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4612 and tiar-2

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_496718.1	Gene:	tiar-2 / 174909	WormBaseID:	WBGene00012904	Length:	434	Species:	Caenorhabditis elegans

Alignment Length:	183	Identity:	49/183 - (26%)
Similarity:	86/183 - (46%)	Gaps:	18/183 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 GGALASGSTGGSGGNSSPDSGKIYIKNLERSIDNKAVYDTFSVFGNILNCNVAKDEDGNSRGYGF 157
            |..||||         |.|...:::.||:.:|.::.:...|:..|.::...:.  .:|.:..|.|
Worm    29 GFQLASG---------SEDPRTLFVANLDPAITDEFLATLFNQIGAVMKAKII--FEGLNDPYAF 82

  Fly   158 VHFDSEEAARAAIEKVNGMLCNNQKVHVV-KFIPRRDREQ----EKATHFKNLYVKNLSEEFTEQ 217
            |.|.....|..|::..||.....:::||. .|.||...|.    |.:.|| :::|.:|..|....
Worm    83 VEFSDHNQATLALQSHNGRELLEKEMHVTWAFEPREPGENRSKPETSRHF-HVFVGDLCSEIDST 146

  Fly   218 HLREMFEPYGRITSHKLMLDEE-GRSRRFGFVAYENPQSALAAVIGLHGKQLG 269
            .|||.|..:|.::..|::.|.. .:.:.:|||:|...:.|..|:..::|..||
Worm   147 KLREAFVKFGEVSEAKIIRDNNTNKGKGYGFVSYPRREDAERAIDEMNGAWLG 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	14/69 (20%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	20/69 (29%)
tiar-2	NP_496718.1	RRM	36..321	CDD:223796	44/167 (26%)
		RRM_SF	42..113	CDD:302621	16/72 (22%)
		RRM_SF	133..207	CDD:302621	19/67 (28%)
		RRM3_TIA1_like	256..326	CDD:240800
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910