DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and etr-1

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_001368521.1	Gene:	etr-1 / 173401	WormBaseID:	WBGene00001340	Length:	589	Species:	Caenorhabditis elegans

Alignment Length:	169	Identity:	48/169 - (28%)
Similarity:	83/169 - (49%)	Gaps:	19/169 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 SSPDSG--KIYIKNLERSIDNKAVYDTFSVFGNILNCNVAKDEDGN-SRGYGFVHF----DSEEA 165
            |.||:.  |:::..:.|..:.......|..:|::.:||:.:|:... |:|..||.|    |:.||
Worm    48 SEPDTDAIKMFVGQIPRQWNETDCRRLFEKYGSVFSCNILRDKSTQASKGCCFVTFYHRKDAIEA 112

  Fly   166 ARAA--IEKVNGMLCNNQKVHVVKFIPRRDREQEKATHFKNLYVKNLSEEFTEQHLREMFEPYGR 228
            ..|.  |:.:.||      .|.|:..| .|.|....   :.|::..||::..|::|||:|..:|.
Worm   113 QGALHNIKVIEGM------HHPVQMKP-ADTENRNE---RKLFIGQLSKKHNEENLREIFAKFGH 167

  Fly   229 ITSHKLMLDEEGRSRRFGFVAYENPQSALAAVIGLHGKQ 267
            |....::.|::|:||...||.:.|...|:.|...:|..|
Worm   168 IEDCSVLRDQDGKSRGCAFVTFTNRSCAVVATKEMHHSQ 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	18/76 (24%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	21/66 (32%)
etr-1	NP_001368521.1	RRM1_CELF1_2_Bruno	54..135	CDD:410040	22/87 (25%)
		PABP-1234	57..>583	CDD:130689	44/160 (28%)
		RRM2_Bruno_like	141..221	CDD:410044	21/69 (30%)
		RRM3_CELF1-6	506..578	CDD:409797
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910