DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4612 and CSTF2

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_001293135.1	Gene:	CSTF2 / 1478	HGNCID:	2484	Length:	597	Species:	Homo sapiens

Alignment Length:	114	Identity:	33/114 - (28%)
Similarity:	59/114 - (51%)	Gaps:	16/114 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   190 PRRDREQEKATHFKNLYVKNLSEEFTEQHLREMFEPYGRITSHKLMLDEE-GRSRRFGFVAYENP 253
            |..||.      .::::|.|:..|.||:.|:::|...|.:.|.:|:.|.| |:.:.:||..|::.
Human     9 PAVDRS------LRSVFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYGFCEYQDQ 67

  Fly   254 QSALAAVIGLHGKQLGDNKFLYVARALSKAERQQEINRKLEERKRQKAG 302
            ::||:|:..|:|::       :..|||.......|.|:  ||.|....|
Human    68 ETALSAMRNLNGRE-------FSGRALRVDNAASEKNK--EELKSLGTG 107

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	24/80 (30%)
CSTF2	NP_001293135.1	PABP-1234	4..352	CDD:130689	33/114 (29%)
		RRM_CSTF2_CSTF2T	18..92	CDD:241115	24/80 (30%)
		CSTF2_hinge	112..191	CDD:373015
		PRK14718	<412..>469	CDD:173181
		CSTF_C	553..593	CDD:373006
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910