DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and AgaP_AGAP001419

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	XP_003435823.1	Gene:	AgaP_AGAP001419 / 1281757	VectorBaseID:	AGAP001419	Length:	532	Species:	Anopheles gambiae

Alignment Length:	203	Identity:	52/203 - (25%)
Similarity:	107/203 - (52%)	Gaps:	21/203 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   107 NSSPDSGKIYIKNLERSIDNKAVYDTF-SVFGNILNCNV--AKDEDGNSRGYGFVHFDSEEAARA 168
            |.|..:.::::.|:.:|...:.:.|.| .:...::...:  :.|:...:||:.|:.::|.:||..
Mosquito   243 NVSVPNLRLFVGNIPKSKGKEEILDEFGKLTAGLVEVIIYSSPDDKKKNRGFCFLEYESHKAASL 307

  Fly   169 AIEKV-NGMLCNNQKVHVVKFI-----PRRDREQEKATHFKNLYVKNLSEEFTEQHLREMFEPYG 227
            |..:: .|.:    ||.....|     |:.:.:::..:..|.|||:||:::.:|:.|:|.||.:|
Mosquito   308 AKRRLGTGRI----KVWNCDIIVDWADPQEEPDEQTMSKVKVLYVRNLTQDTSEEKLKESFEQFG 368

  Fly   228 RITSHKLMLDEEGRSRRFGFVAYENPQSALAAVIGLHGKQL-GDNKFLYVARALSKAERQQEINR 291
            |:...|.:.|       :.||.:|:..:|:.|:..|.||:: |.|..:.:|:..|..::::||.|
Mosquito   369 RVERVKKIKD-------YAFVHFEDRDNAVKAMKDLDGKEVGGSNIEVSLAKPPSDKKKKEEILR 426

  Fly   292 KLEERKRQ 299
            ..|.|..|
Mosquito   427 ARERRMTQ 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	15/73 (21%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	26/80 (33%)
AgaP_AGAP001419	XP_003435823.1	RRM1_hnRNPR_like	167..245	CDD:240695	1/1 (100%)
		RRM2_hnRNPR_like	248..329	CDD:240696	16/84 (19%)
		RRM3_hnRNPR_like	343..414	CDD:240697	26/77 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910