DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and AgaP_AGAP001538

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	XP_321584.5	Gene:	AgaP_AGAP001538 / 1281638	VectorBaseID:	AGAP001538	Length:	408	Species:	Anopheles gambiae

Alignment Length:	191	Identity:	53/191 - (27%)
Similarity:	94/191 - (49%)	Gaps:	23/191 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 IYIKNLERSIDNKAVYDTFSVFGNILNCNVAKDE-DGNSRGYGFVHFDSEEAARAAIEKVNGMLC 178
            ||:..|:..:....:::.|...|.::|.::.||. ....:|||||.|..||.|..||:.:|
Mosquito    15 IYVGGLDDKVTETLLWELFVQSGPVVNVHMPKDRVTQMHQGYGFVEFLGEEDADYAIKIMN---- 75

  Fly   179 NNQKVHVVKFIPRRDREQEKATHFK------NLYVKNLSEEFTEQHLREMFEPYGRI-TSHKLML 236
                  ::|...:..|..:.:.|.|      |:::.||..|..|:.|.:.|..:|.| .:.|:|.
Mosquito    76 ------MIKLYGKPIRVNKASAHQKSLDVGANIFIGNLDLEVDEKLLYDTFSAFGVILQTPKIMR 134

  Fly   237 D-EEGRSRRFGFVAYENPQSALAAVIGLHGKQLGDNKFLYVARAL---SKAERQQEINRKL 293
            | |.|.|:.|.|:.:.:.:::.||:..::|:.| .|:.:.|:.|.   ||.||......:|
Mosquito   135 DPETGNSKGFAFINFASFEASDAAMDAMNGQYL-CNRPISVSYAFKKDSKGERHGSAAERL 194

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	20/70 (29%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	25/90 (28%)
AgaP_AGAP001538	XP_321584.5	RRM1_SF3B4	15..88	CDD:240780	22/82 (27%)
AgaP_AGAP001538	XP_321584.5	RRM2_SF3B4	99..181	CDD:240781	24/82 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910