DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and AgaP_AGAP001643

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	XP_321453.3	Gene:	AgaP_AGAP001643 / 1281529	VectorBaseID:	AGAP001643	Length:	1196	Species:	Anopheles gambiae

Alignment Length:	160	Identity:	34/160 - (21%)
Similarity:	68/160 - (42%)	Gaps:	27/160 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   107 NSSPDSGKIYIKNLERSIDNKAVYDTFSVFGNILNCNVAKDEDGNSRGYGFVHFD--SEEAARAA 169
            |:......:::.|:...:..:.:.|.|:.:|.:.|.:.|:     .:.:|.|:|:  :.:.|..|
Mosquito  1034 NTKHQKHTVFVGNVNSKMSEREIEDIFARYGRLENVDFAR-----RKRFGEVYFNYSNRDHAFKA 1093

  Fly   170 IEKVNGMLCNNQKVHVVKFIPRRDR---EQEKATHFKNLYV-KNLSEEFTEQHLREMFEPYGRIT 230
            :|..|           ||.:.||.|   ..||..|.:...: ..:.:...||.:.:.:|.||.|.
Mosquito  1094 LEMNN-----------VKIMGRRLRVSFNSEKPIHREGYTIYYTMRQPTDEQTIYQSYESYGEID 1147

  Fly   231 SHKLMLDEEGRSRRFGFVAYENPQSALAAV 260
            .  :...:.|   .||.:.:...:||..|:
Mosquito  1148 F--IWYPDNG---LFGTITFRRAESATEAL 1172

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	13/71 (18%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	12/60 (20%)
AgaP_AGAP001643	XP_321453.3	RRM_SF	7..77	CDD:240668
		RRM	<90..>199	CDD:223796
		RRM_SF	92..157	CDD:240668
		RRM_SF	281..339	CDD:240668
		RRM_SF	504..573	CDD:240668
		EBP50_C	<764..840	CDD:286142
		RRM_SF	1042..1109	CDD:240668	18/82 (22%)
		RRM_SF	1131..1184	CDD:302621	12/47 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910