DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and AgaP_AGAP001883

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	XP_321180.5	Gene:	AgaP_AGAP001883 / 1281239	VectorBaseID:	AGAP001883	Length:	396	Species:	Anopheles gambiae

Alignment Length:	198	Identity:	58/198 - (29%)
Similarity:	98/198 - (49%)	Gaps:	21/198 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 HSANVGVGVGGG----ALASGSTGGSGGNSSPDSGK--IYIKNLERSIDNKAVYDTFSVFGNILN 141
            :.||.|.|.|||    .:|.|:.|| ||.||.::.:  :.:..|.:::..:.:...||..|.:.:
Mosquito    39 NGANGGGGGGGGEAGQTVAGGAAGG-GGQSSDNNSRTNLIVNYLPQTMTEEEIRSLFSSVGEVES 102

  Fly   142 CNVAKDED--------GNSRGYGFVHFDSEEAARAAIEKVNGMLCNNQKVHVVKFIPRRDREQEK 198
            ..:.:|::        |.|.|||||::...:.|..|:..:||:...| ||..|.|.    |...:
Mosquito   103 VKLVRDKNVIYPGQPKGQSLGYGFVNYHRPQDAEQAVNVLNGLRLQN-KVLKVSFA----RPSSE 162

  Fly   199 ATHFKNLYVKNLSEEFTEQHLREMFEPYGR-ITSHKLMLDEEGRSRRFGFVAYENPQSALAAVIG 262
            .....|||:..|.:..|::.|..:|.|||. |||..|:.|...:.:..||:.::..:.|..|:..
Mosquito   163 GIKGANLYISGLPKTITQEELETIFRPYGEIITSRVLIQDGNDKPKGVGFIRFDQRKEAERAIQA 227

  Fly   263 LHG 265
            |:|
Mosquito   228 LNG 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	19/77 (25%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	21/65 (32%)
AgaP_AGAP001883	XP_321180.5	ELAV_HUD_SF	71..396	CDD:273741	43/165 (26%)
		RRM1_Hu	73..157	CDD:241094	20/84 (24%)
		RRM2_Hu	167..245	CDD:241096	21/64 (33%)
		RRM3_Hu	314..391	CDD:240823
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910