DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4612 and AgaP_AGAP001930

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	XP_003435970.1	Gene:	AgaP_AGAP001930 / 1281194	VectorBaseID:	AGAP001930	Length:	412	Species:	Anopheles gambiae

Alignment Length:	175	Identity:	51/175 - (29%)
Similarity:	83/175 - (47%)	Gaps:	29/175 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 DSGKIYIKNL--ERSIDNKAVYDTFSVFGNILNCNVAK-DEDGNSRGYGFVHFDSEEAARAAIEK 172
            :.||:::..|  |.|.:|...|  ||.:|.:::|.|.| :|.|.|||:|||.|...|....|:|.
Mosquito    16 EKGKLFVGGLSWETSHENLQRY--FSRYGEVIDCVVMKNNETGRSRGFGFVTFADPENVERALEN 78

  Fly   173 ---------VNGMLCNNQKVHVVKFIPRRDREQEKATHFKNLYVKNLSEEFTEQHLREMFEPYGR 228
                     ::...||          ||...:.::...:..:::..|....||..||..|..||.
Mosquito    79 GPHTLDGRTIDPKPCN----------PRSQHKPKRTGGYPKVFLGGLPPNITETDLRSFFCRYGT 133

  Fly   229 ITSHKLMLDEE-GRSRRFGFVAYENPQSALAAV----IGLHGKQL 268
            :....:|.|:| .:||.|||:::||..:...|.    :.:.|||:
Mosquito   134 VMEVVIMYDQEKKKSRGFGFLSFENESAVERATTDHFVHISGKQV 178

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	25/81 (31%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	22/72 (31%)
AgaP_AGAP001930	XP_003435970.1	RRM_SF	19..100	CDD:302621	28/92 (30%)
AgaP_AGAP001930	XP_003435970.1	RRM2_DAZAP1	106..185	CDD:240773	22/73 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910