DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and AgaP_AGAP010496

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	XP_314469.4	Gene:	AgaP_AGAP010496 / 1275237	VectorBaseID:	AGAP010496	Length:	258	Species:	Anopheles gambiae

Alignment Length:	217	Identity:	46/217 - (21%)
Similarity:	82/217 - (37%)	Gaps:	60/217 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 KIYIKNLERSIDNKAVYDTFSVFGNILNCNVAKDEDGNSRG--YGFVHFDSEEAARAAIEKVNGM 176
            :||:.||...|..|.:.|.|..||.:...::.     |.||  :.||.|:....|..|::..:|.
Mosquito     9 RIYVGNLPPDIRTKDIQDLFHKFGKVTFVDLK-----NRRGPPFAFVEFEDARDADDAVKARDGY 68

  Fly   177 LCNNQKVHVVKFIPR--------------RDREQE-----------KATHFKNLYVKNLSEEFTE 216
            ..:..::.|.  .||              .||...           :.:.|: :.|..|....:.
Mosquito    69 DYDGYRLRVE--FPRGGGPGSYRGSRQGNSDRNSRGGDRNNRGPPARRSQFR-VMVTGLPSSGSW 130

  Fly   217 QHLREMFEPYGRITSHKLMLDEEGRSRRFGFVAYENPQSALAAVIGLHGKQLGDNKFLYVARALS 281
            |.|::.....|.:....:..|..|...   |:.:|:.:.|:        |:|.|::|
Mosquito   131 QDLKDHMREAGDVCFADVYKDGTGVVE---FLRHEDMKYAI--------KKLDDSRF-------- 176

  Fly   282 KAERQQEINRKL---EERKRQK 300
               |..|:::|.   .||:|:|
Mosquito   177 ---RSHEVSKKTRGEREREREK 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	19/71 (27%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	15/79 (19%)
AgaP_AGAP010496	XP_314469.4	RRM	<1..183	CDD:223796	41/203 (20%)
		RRM1_SRSF1	9..81	CDD:241041	20/78 (26%)
		RRM2_SRSF1_like	117..180	CDD:241045	16/85 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910