DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and AgaP_AGAP011092

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	XP_309558.3	Gene:	AgaP_AGAP011092 / 1270836	VectorBaseID:	AGAP011092	Length:	634	Species:	Anopheles gambiae

Alignment Length:	191	Identity:	109/191 - (57%)
Similarity:	146/191 - (76%)	Gaps:	4/191 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 GKIYIKNLERSIDNKAVYDTFSVFGNILNCNVAKDEDGNSRGYGFVHFDSEEAARAAIEKVNGML 177
            |.::||||::.|||||:|||||.|||||:|.||:||.|.|:|||||||::||:|..:||||||||
Mosquito    90 GNVFIKNLDKKIDNKAMYDTFSAFGNILSCKVAQDEKGQSKGYGFVHFETEESANTSIEKVNGML 154

  Fly   178 CNNQKVHVVKFIPRRDREQ---EKATHFKNLYVKNLSEEFTEQHLREMFEPYGRITSHKLMLDEE 239
            .|.:||:|.:||.|::||:   |||..|.|:||||..|:.||:.||:|||.:|.||||::| .::
Mosquito   155 LNEKKVYVGRFISRKEREKELGEKAKLFTNVYVKNFGEDLTEEALRDMFEKFGPITSHRVM-TKD 218

  Fly   240 GRSRRFGFVAYENPQSALAAVIGLHGKQLGDNKFLYVARALSKAERQQEINRKLEERKRQK 300
            |:||.|||||:|.|:.|..||..|:||:|.|.|.|||.||..|.|||.|:.|:.|:.|.::
Mosquito   219 GKSRGFGFVAFEKPEDAEEAVQKLNGKELSDGKVLYVGRAQKKNERQMELKRRFEQLKMER 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	47/69 (68%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	44/79 (56%)
AgaP_AGAP011092	XP_309558.3	PABP-1234	2..624	CDD:130689	109/191 (57%)
		RRM1_I_PABPs	3..82	CDD:240824
		RRM2_I_PABPs	88..164	CDD:240825	49/73 (67%)
		RRM3_I_PABPs	182..261	CDD:240826	44/79 (56%)
		RRM4_I_PABPs	285..362	CDD:240827
		PABP	556..623	CDD:279051
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1027234at2759
OrthoFinder	1	1.000	-	-		FOG0000294
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24012
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020