DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4612 and HNRNPA0

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_006796.1	Gene:	HNRNPA0 / 10949	HGNCID:	5030	Length:	305	Species:	Homo sapiens

Alignment Length:	159	Identity:	45/159 - (28%)
Similarity:	74/159 - (46%)	Gaps:	13/159 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 KIYIKNLERSIDNKAVYDTFSVFGNILNC-NVAKDEDGNSRGYGFVHFDSEEAARAAI----EKV 173
            |::|..|........:...|..||.:.:| .|...:...||.:|||.:.:.|.|.||:    ..|
Human     8 KLFIGGLNVQTSESGLRGHFEAFGTLTDCVVVVNPQTKRSRCFGFVTYSNVEEADAAMAASPHAV 72

  Fly   174 NGMLCNNQKVHVVKFIPRRDREQEKA-THFKNLYVKNLSEEFTEQHLREMFEPYGRITSHKLMLD 237
            :|     ..|.:.:.:.|.|..:..| ...|.|:|..|..:..|..|.|.|..:|.:...:::.|
Human    73 DG-----NTVELKRAVSREDSARPGAHAKVKKLFVGGLKGDVAEGDLIEHFSQFGTVEKAEIIAD 132

  Fly   238 EE-GRSRRFGFVAYENPQSA-LAAVIGLH 264
            :: |:.|.||||.::|..:| .|||:..|
Human   133 KQSGKKRGFGFVYFQNHDAADKAAVVKFH 161

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	19/74 (26%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	22/65 (34%)
HNRNPA0	NP_006796.1	RRM1_hnRNPA0	5..83	CDD:240772	20/79 (25%)
		RRM2_hnRNPA0	99..178	CDD:241023	21/63 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	174..214
		HnRNPA1	255..>269	CDD:314495
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	262..305
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910