DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and Cstf2

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_001345982.1	Gene:	Cstf2 / 108062	MGIID:	1343054	Length:	603	Species:	Mus musculus

Alignment Length:	115	Identity:	33/115 - (28%)
Similarity:	63/115 - (54%)	Gaps:	12/115 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   189 IPRRDREQEKATHFKNLYVKNLSEEFTEQHLREMFEPYGRITSHKLMLDEE-GRSRRFGFVAYEN 252
            :|.||...:::  .::::|.|:..|.||:.|:::|...|.:.|.:|:.|.| |:.:.:||..|::
Mouse     4 LPVRDPAVDRS--LRSVFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYGFCEYQD 66

  Fly   253 PQSALAAVIGLHGKQLGDNKFLYVARALSKAERQQEINRKLEERKRQKAG 302
            .::||:|:..|:|::       :..|||.......|.|:  ||.|....|
Mouse    67 QETALSAMRNLNGRE-------FSGRALRVDNAASEKNK--EELKSLGTG 107

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	24/80 (30%)
Cstf2	NP_001345982.1	RRM	<7..332	CDD:330708	32/112 (29%)
		RRM_CSTF2_CSTF2T	18..92	CDD:241115	24/80 (30%)
		CSTF2_hinge	113..191	CDD:316816
		Rnc	<418..>475	CDD:330804
		CSTF_C	559..599	CDD:316795
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910