DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and elavl4

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	XP_012815941.1	Gene:	elavl4 / 100125165	XenbaseID:	XB-GENE-948210	Length:	430	Species:	Xenopus tropicalis

Alignment Length:	220	Identity:	53/220 - (24%)
Similarity:	91/220 - (41%)	Gaps:	48/220 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 VGGGALASGSTGGSG-----------GNSSPDSGKIYIKN-LERSIDNKAVYDTFSVFGNILNCN 143
            |..|..::.|.|.|.           |.::.||....|.| |.:::..:.....|...|.|.:|.
Frog    47 VSNGPTSNTSNGPSSNSRNCPSPMQTGAATDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCK 111

  Fly   144 VAKDE------------------------------DGNSRGYGFVHFDSEEAARAAIEKVNGMLC 178
            :.:|:                              .|.|.|||||::...:.|..||..:||:..
Frog   112 LVRDKITGTQFEEHFKDLATGTKWKPLTEEGPIFGKGQSLGYGFVNYIDPKDAEKAINTLNGLRL 176

  Fly   179 NNQKVHVVKFIPRRDREQEKATHFKNLYVKNLSEEFTEQHLREMFEPYGRITSHKLMLDE-EGRS 242
            ..:.:.|     ...|....:....||||..|.:..|::.|.::|..||||.:.::::|: .|.|
Frog   177 QTKTIKV-----SYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVS 236

  Fly   243 RRFGFVAYENPQSALAAVIGLHGKQ 267
            |..||:.::....|..|:.||:|::
Frog   237 RGVGFIRFDKRIEAEEAIKGLNGQK 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	20/100 (20%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	23/67 (34%)
elavl4	XP_012815941.1	ELAV_HUD_SF	78..429	CDD:273741	47/189 (25%)
		RRM1_Hu	80..186	CDD:241094	21/110 (19%)
		RRM_SF	191..280	CDD:302621	23/71 (32%)
		RRM3_HuD	344..429	CDD:241100
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910