DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and celf2

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	XP_012813883.1	Gene:	celf2 / 100125022	XenbaseID:	XB-GENE-963640	Length:	559	Species:	Xenopus tropicalis

Alignment Length:	261	Identity:	65/261 - (24%)
Similarity:	114/261 - (43%)	Gaps:	37/261 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 AAVLGRHGHNSLGSGHTSTSSHSANVGVGVGGGALASGSTGGSGGNSSPDSGKIYIKNLERSIDN 126
            :||..|:....|.|....||...:|.......|||      .......||:.|:::..:.||...
Frog    24 SAVTMRNEELLLSSLACFTSEIESNGTTNKMNGAL------DHSDQPDPDAIKMFVGQIPRSWSE 82

  Fly   127 KAVYDTFSVFGNILNCNVAKDEDGN---SRGYGFVHFDSEEAARAAIEKVNGMLCNNQKVHVVKF 188
            |.:.|.|..:|.:...||.:|...|   |:|..||.|.:.   :||:|..|.:       |.:|.
Frog    83 KELKDLFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTR---KAALEAQNAL-------HNIKT 137

  Fly   189 IP---------RRDREQEKATHFKNLYVKNLSEEFTEQHLREMFEPYGRITSHKLMLDEEGRSRR 244
            :|         ..|.|:..|...:.|::..:|::..|..:|.||.|:|:|...:::...:|.||.
Frog   138 LPGMHHPIQMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFSPFGQIEECRILRGPDGLSRA 202

  Fly   245 ----FGFVAYENPQSALAAVIGLHGKQL--GDNKFLYVARALSKAERQQEINRKLEERKRQKAGQ 303
                ..||.:.....|..|:..:|..|.  |.:..:.|..|.::.:::|   |:|:::..|:..|
Frog   203 SQHCCAFVTFSTRAMAQNAIKAMHQSQTMEGCSSPIVVKFADTQKDKEQ---RRLQQQLAQQMQQ 264

  Fly   304 I 304
            :
Frog   265 L 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	19/72 (26%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	21/85 (25%)
celf2	XP_012813883.1	RRM1_CELF1_2_Bruno	68..151	CDD:241075	23/92 (25%)
		ELAV_HUD_SF	71..554	CDD:273741	51/208 (25%)
		RRM2_CELF1_2	160..244	CDD:241078	20/83 (24%)
		RRM3_CELF1_2	469..558	CDD:241082
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910