DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4612 and celf5

DIOPT Version :9

Sequence 1:	NP_001246493.1	Gene:	CG4612 / 37914	FlyBaseID:	FBgn0035016	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	NP_001090639.1	Gene:	celf5 / 100036604	XenbaseID:	XB-GENE-494002	Length:	486	Species:	Xenopus tropicalis

Alignment Length:	349	Identity:	59/349 - (16%)
Similarity:	96/349 - (27%)	Gaps:	185/349 - (53%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 SGSTGGSGGNSSPDSGKIYIKNLERSIDNKAVYDTFSVFGNILNCNVAKDEDGNSRGYGFVHFDS 162
            |.|.||        ..|:::..|.:....:.|...|..||:|..|:|.:..||:|:|..||.|.|
Frog   128 SESRGG--------DRKLFVGMLSKQQSEEEVTSMFQAFGSIEECSVLRGPDGSSKGCAFVKFSS 184

  Fly   163 EEAARAAIEKVNGM--------------------------------------------------- 176
            ...|:|||:.::|.
Frog   185 HAEAQAAIQALHGSQTMPGASSSLVVKFADTDKERTLRRMQQMVGQLGIFTPSLALPISPYSAYA 249

  Fly   177 --------------------------LCNNQKVHVVKF--------------------------- 188
                                      .|:.|::..|..
Frog   250 QALMQQQTTVLSTSHGSYLSPSVAFPSCHIQQIGAVNLNGLPAAPITPASGLHSPPVIGTAAVPG 314

  Fly   189 ------------------IPRRDR----------------------------------------- 194
                              .|..|.
Frog   315 LVAPLTNGFPGLVPFPSSHPALDTIYTNSIVPYPAQSPALTVESLHPSFTGVQQYSAIYPTAALT 379

  Fly   195 -------------EQEKATHFKNLYVKNLSEEFTEQHLREMFEPYGRITSHKLMLDE-EGRSRRF 245
                         :|.:.....||::.:|.:||.:..|.:||.|:|.|.|.|:.:|. ..:|:.|
Frog   380 PVTHSTPQPPPILQQREGPEGCNLFIYHLPQEFGDNELTQMFLPFGNIISSKVFMDRATNQSKCF 444

  Fly   246 GFVAYENPQSALAAVIGLHGKQLG 269
            |||:::||.||..|:..::|.|:|
Frog   445 GFVSFDNPSSAQTAIQAMNGFQIG 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4612	NP_001246493.1	RRM2_I_PABPs	115..185	CDD:240825	23/146 (16%)
CG4612	NP_001246493.1	RRM3_I_PABPs	202..282	CDD:240826	27/69 (39%)
celf5	NP_001090639.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..39
		RRM1_CELF3_4_5_6	42..128	CDD:241076	59/349 (17%)
		PABP-1234	<49..374	CDD:130689	31/253 (12%)
		RRM2_CELF3_4_5_6	134..214	CDD:241079	22/79 (28%)
		RRM3_CELF3_4_5_6	397..475	CDD:241083	27/72 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910