Protein Alignment Letm1 and LETM1

DIOPT Version :10

• Sequence 1: NP_611922.1
• Gene: Letm1 / 37912
• FlyBaseID: FBgn0284252
• Length: 1013
• Species: Drosophila melanogaster
• Sequence 2: NP_001030897.1
• Gene: LETM1 / 825151
• AraportID: AT3G59820
• Length: 760
• Species: Arabidopsis thaliana
• Alignment Length: 834
• Identity: 254/834 - (30%)
• Similarity: 403/834 - (48%)
• Gaps: 135/834 - (16%)

  Fly     3 ALLRHKGRNLRTSHLAQNVYKRFLKS------------NCCACSSVN---VTDEPAKEDE-LPRR 51
            |::|.|  |:.:.:|  |||.|.::|            :....|.:|   |..:|..|.: ..||
plant     5 AIVRRK--NIISDYL--NVYARSIQSFQYIGNSSQTVHSHAYHSGINRPPVETKPVTEHKSFTRR 65

  Fly    52 SASTSVLELSRSLGTYRRFQPHANYGYDYSGYGFRHLHTSRTL----LETSSSKIDATVKKLKNQ 112
            .   .:|.|||: |.:.|    :.:|:..||:|:.......:|    :..|.........|...:
plant    66 D---GLLLLSRN-GYFNR----SFHGFHSSGFGYGSSEVGPSLGMRYMSLSIRNATTVAAKKPEE 122

  Fly   113 QKEKVEEIMKEVANGQAA-------AVRASSAATATASSEKGQNASATAGSTSATASTTSL-AKT 169
            :.:||:|:.|   |.:.|       ||.:.|:..|.|.:::.|.:...|.|....|....| ...
plant   123 EDKKVDELAK---NRKEASPEECDQAVESLSSVKAKAKAKRLQESKKVARSIVQRAWAIVLKIGP 184

  Fly   170 ADKSVAKPKK---PLRTRIW-----DELVHYYHGFRLLFIDVAICSKLLWRVLNGKTLTRRENKQ 226
            |.|:||...:   ..:...|     ..|.||:.|.:||:.|..|.|:||.::..||:|:|||.:|
plant   185 AIKAVASMNRADWAKKLTHWKHEFVSTLKHYWLGTKLLWADTRISSRLLLKLAGGKSLSRRERQQ 249

  Fly   227 LQRTTSDLFRLIPFSVFIIVPFMELLLPLFIKFFPGMLPSTFQTSTDRQEKLRQSLSVRLEVAKF 291
            |.|||:|:|||:||:|||:|||||.|||:|:|.||.|||||||.....:|.|::.|..|:|.|||
plant   250 LTRTTADIFRLVPFAVFILVPFMEFLLPVFLKLFPNMLPSTFQDKMKEEEALKRKLLARIEYAKF 314

  Fly   292 LQQTLDQMPVQHKEHSSEEAKQ----FEAFFTKIRNPTEPVSNDEIIKFAKRFDDEITLDSLSRE 352
            ||:|..:|..:.|...:.|.||    .:.|..|:|. .:.|.|||::.|||.|:||:|||::||.
plant   315 LQETAREMAKEVKHSRTGEVKQTAEDLDEFLDKVRR-GQIVHNDELLGFAKLFNDELTLDNISRP 378

  Fly   353 QLAALCRVLELNTIGTTTLLRFQLRLKLRSLATDDRVIAREGVDSLDLLELQQACKARGMRAYGL 417
            :|.::|:.:.::..||...||:.||.:|||:..||::|..||||||...||::.|:.|||  .||
plant   379 RLVSMCKYMGISPYGTDAYLRYMLRKRLRSIKEDDKLIRAEGVDSLSEAELREDCRERGM--LGL 441

  Fly   418 TE-ERLRFQLKEWIDLSLNEQVPPTLLLLSRTMLISDDSITTDKLKETIRVLPDAVGAHTRHAIG 481
            .. |.:|.||::|:|||||..||.:||:|||...::......|.::.|:..|||.|.........
plant   442 VSVEEMRQQLRDWMDLSLNHSVPSSLLILSRAFTVAGRVKAEDAVRATLSSLPDEVVDTVGITSL 506

  Fly   482 ESEGKV-DNKTKIEIIKEEERKIREEREEEREETIAKRSAIK--------EEIPAPYVFAEKLSG 537
            .||..| :.:.|:|.::.:|..|:||.|:|.|| :.:...:|        :|:..|.....:...
plant   507 PSEDPVSERRRKLEYLEMQEELIKEEEEKEEEE-LTRIKDVKGGDEDKALQEMTIPTASEAQEQA 570

  Fly   538 SQDLLDHKEQSSVSETDKGISSTDVQLLSEALKTLSSDKQLVVEKET-IKELKEELADYKEDVEE 601
            ...:|:.::              |:..||.||..|:|...:..|:|. ::.:|:|:..|...||
plant   571 RARVLEQQD--------------DLCKLSRALGVLASASSVCREREEFLRLVKKEVEFYNTMVE- 620

  Fly   602 LREVRQVVKEPVRESRAAKLLYNRVNKMISQLDNVLNDLEARQHQIKQAESSDYAASSPTVEPQQ 666
                    :|.|...:||...|......|.|.|.|                    |.:..|....
plant   621 --------REDVDGEKAAMKAYKAARVDIDQADEV--------------------AEADEVSSAL 657

  Fly   667 MVHIDELVATIRRMKEASDEERFKVVGDLLVKLDADKDGVISVNEITKAVQSIDREATNIDKKQL 731
            |..:|.|   |:.:::..|:...| :|.....||.|:||.::.:|:..|...:.....|
plant   658 MEKVDGL---IQNLEKEIDDVDIK-IGKGWQLLDRDRDGKVTPDEVAAAAMYLKDTLAN------ 712

  Fly   732 EEFTELLSKLASRR------RHEEIVHIDDLMNNIKVLKETSDEARLKHIEAVL 779
            :...:|:|.|:..:      ||.::..|.      |..:...:..|:|..|.:|
plant   713 DGLQQLISSLSKDKGKNYGGRHCKVGEIG------KQARRKCNGRRIKLKEIIL 760

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Letm1	NP_611922.1	LETM1_RBD	219..450	CDD:462258	116/235 (49%)
		PRK03918	<543..>916	CDD:235175	51/244 (21%)
LETM1	NP_001030897.1	PTZ00121	<116..>175	CDD:173412	15/61 (25%)
		LETM1_RBD	242..475	CDD:462258	116/235 (49%)