Protein Alignment Letm1 and Letm2

DIOPT Version :10

• Sequence 1: NP_611922.1
• Gene: Letm1 / 37912
• FlyBaseID: FBgn0284252
• Length: 1013
• Species: Drosophila melanogaster
• Sequence 2: XP_006509186.1
• Gene: Letm2 / 270035
• MGIID: 2444979
• Length: 516
• Species: Mus musculus
• Alignment Length: 348
• Identity: 152/348 - (43%)
• Similarity: 229/348 - (65%)
• Gaps: 4/348 - (1%)

  Fly   153 TAGSTSATASTTSLAKTADKSVAKPKKPLRTRIWDELVHYYHGFRLLFIDVAICSKLLWRVLNGK 217
            |....:|:...|..|||   ...:.|:.||.:|.:||.:||.||.||:||..:.::::||:|:|.
Mouse    95 TGKPKAASPQPTKEAKT---ETTEEKRSLRQKIVNELKYYYKGFSLLWIDTKVAARIVWRLLHGN 156

  Fly   218 TLTRRENKQLQRTTSDLFRLIPFSVFIIVPFMELLLPLFIKFFPGMLPSTFQTSTDRQEKLRQSL 282
            .|||||.::|.||.:|:|||:||.|||||||||.|:|:|:|.||.||||||::.:.::||.::::
Mouse   157 ALTRRERRRLLRTCADVFRLVPFMVFIIVPFMEFLIPVFLKLFPDMLPSTFESESKKEEKQKKTM 221

  Fly   283 SVRLEVAKFLQQTLDQMPVQHKEHSSEEAKQFEAFFTKIRNPTEPVSNDEIIKFAKRFDDEITLD 347
            :.:||:|||||:|:.:|..:::....:.:.|..::..:::...:| |..||::|:|.|.|::.|:
Mouse   222 AAKLEIAKFLQETMTEMARRNRAKLGDASSQLSSYVKQVQTGHKP-STKEIVRFSKLFKDQLALE 285

  Fly   348 SLSREQLAALCRVLELNTIGTTTLLRFQLRLKLRSLATDDRVIAREGVDSLDLLELQQACKARGM 412
            .|.|.||.|||::|||.|.||..||||||.:.|:|:..||.:||:|||.:|.:.|||.||:||||
Mouse   286 HLDRPQLVALCKLLELQTFGTNNLLRFQLLMTLKSIKADDEIIAKEGVKALSVSELQSACRARGM 350

  Fly   413 RAYGLTEERLRFQLKEWIDLSLNEQVPPTLLLLSRTMLISDDSITTDKLKETIRVLPDAVGAHTR 477
            |:.|||||:|..||..|:||.|.|.|||:|||||||..:.|......:|...|......:|..|.
Mouse   351 RSLGLTEEQLCQQLTGWLDLHLKENVPPSLLLLSRTFYLIDVKPKPIELPPNIETPKPNLGIPTP 415

  Fly   478 HAIGESEGKVDNKTKIEIIKEEE 500
            ......|...|:..:::..|:||
Mouse   416 PPPESKENLTDSAPQLKGTKDEE 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Letm1	NP_611922.1	LETM1_RBD	219..450	CDD:462258	118/230 (51%)
		PRK03918	<543..>916	CDD:235175
Letm2	XP_006509186.1	LETM2_N	1..109	CDD:466042	3/13 (23%)
		LETM1_RBD	171..388	CDD:462258	110/217 (51%)