Protein Alignment Prosalpha4T2 and PRE8

DIOPT Version :10

• Sequence 1: NP_611920.1
• Gene: Prosalpha4T2 / 37910
• FlyBaseID: FBgn0017556
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: NP_013618.1
• Gene: PRE8 / 854882
• SGDID: S000004557
• Length: 250
• Species: Saccharomyces cerevisiae
• Alignment Length: 254
• Identity: 80/254 - (31%)
• Similarity: 131/254 - (51%)
• Gaps: 14/254 - (5%)

  Fly     1 MAQRYDRAVTIYSPDGHLLQVEYAQEAVRRGSTVMGLRTNNAIVIGVEKRSVGDLQEERMVRKIC 65
            |..||..::|.:||.|.|.|::||..||::|.|.:|::..|.:||..||:|...|.....:.|:.
Yeast     1 MTDRYSFSLTTFSPSGKLGQIDYALTAVKQGVTSLGIKATNGVVIATEKKSSSPLAMSETLSKVS 65

  Fly    66 MLDDHVVMTFSGLTADARILVSRAQMEAQS--HRLNFEKPTTVEYITRYIAQLKQNYTQSNGRRP 128
            :|...:...:||:..|.|:||.:::..|.:  .|:..|.|.| :.:...:|::.|..|||.|.||
Yeast    66 LLTPDIGAVYSGMGPDYRVLVDKSRKVAHTSYKRIYGEYPPT-KLLVSEVAKIMQEATQSGGVRP 129

  Fly   129 FGLSCLVGGFDEDGTPHLFQTDPSGIFYEWRANTTGRSSQPVRDYMEKHADEILTIADEAAAIKH 193
            ||:|.|:.|.||.....|:|.||||.::.|:|...|:.|...:.::||..::.|.:.|   || |
Yeast   130 FGVSLLIAGHDEFNGFSLYQVDPSGSYFPWKATAIGKGSVAAKTFLEKRWNDELELED---AI-H 190

  Fly   194 IVRTLVSVS---SLNHTQMEVAVLKYRQPLRMIDHQVLAD----LERTVRREIEDEAEA 245
            |....:..|   ..|...:|:|::....|..:....:..|    ..:...:||.|..||
Yeast   191 IALLTLKESVEGEFNGDTIELAIIGDENPDLLGYTGIPTDKGPRFRKLTSQEINDRLEA 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha4T2	NP_611920.1	Ntn_hydrolase	5..214	CDD:469781	71/213 (33%)
PRE8	NP_013618.1	proteasome_alpha_type_2	5..247	CDD:239719	76/246 (31%)