DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha4T2 and PUP1

DIOPT Version :9

Sequence 1:	NP_001286844.1	Gene:	Prosalpha4T2 / 37910	FlyBaseID:	FBgn0017556	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_014800.3	Gene:	PUP1 / 854328	SGDID:	S000005683	Length:	261	Species:	Saccharomyces cerevisiae

Alignment Length:	209	Identity:	48/209 - (22%)
Similarity:	84/209 - (40%)	Gaps:	17/209 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 YSPDGHLLQVEYAQ-EAVRRGSTVMGLRTNNAIVIGVEKRSV-GDLQEERMVRKICMLDDHVVMT 74
            |..:..|.:..:.| :|...|:|::|::.||.:||..:.||. |.:..::...|:..:...:...
Yeast     9 YQRNNFLAENSHTQPKATSTGTTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCA 73

  Fly    75 FSGLTADARILVSRAQMEAQSHRL-NFEKPTTVEYITRYIAQLKQNYTQSNGRRPFGLSCLVGGF 138
            .:|..||...:........:.|.| ...:|..|.    .:..|||:..:..|.  .|...:|.|.
Yeast    74 GAGTAADTEAVTQLIGSNIELHSLYTSREPRVVS----ALQMLKQHLFKYQGH--IGAYLIVAGV 132

  Fly   139 DEDGTPHLFQTDPSGIFYEWRANTTGRSSQPVRDYMEKH------ADEILTIADEAAAIKHIVRT 197
            |..|: |||.....|........:.|..|......:|.|      .:|.:.:|.:|.. ..|...
Yeast   133 DPTGS-HLFSIHAHGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQ-AGIWND 195

  Fly   198 LVSVSSLNHTQMEV 211
            |.|.|:::...||:
Yeast   196 LGSGSNVDVCVMEI 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha4T2	NP_001286844.1	arc_protsome_A	5..215	CDD:163366	48/209 (23%)
Prosalpha4T2	NP_001286844.1	Ntn_hydrolase	5..214	CDD:294319	48/209 (23%)
PUP1	NP_014800.3	proteasome_beta_type_7	30..219	CDD:239732	43/188 (23%)
PUP1	NP_014800.3	Pr_beta_C	223..257	CDD:403609
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810