DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha4T2 and psmb7

DIOPT Version :9

Sequence 1:	NP_001286844.1	Gene:	Prosalpha4T2 / 37910	FlyBaseID:	FBgn0017556	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	XP_021324576.1	Gene:	psmb7 / 64278	ZFINID:	ZDB-GENE-001208-4	Length:	286	Species:	Danio rerio

Alignment Length:	227	Identity:	49/227 - (21%)
Similarity:	90/227 - (39%)	Gaps:	30/227 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 AVTIYSPDGH---------LLQVE-----YAQEAVRR-GSTVMGLRTNNAIVIGVEKRSV-GDLQ 56
            :|..|.|.|.         ||:.:     ::..|.|: |:|:.|:...:.:|:|.:.|:. |.:.
Zfish     5 SVCQYQPGGFSFENCRRNALLEADITKLGFSSPAARKTGTTICGIVYKDGVVLGADTRATEGMIV 69

  Fly    57 EERMVRKICMLDDHVVMTFSGLTADARILVSRAQMEAQSHRLNFEKPTTVEYITRYIAQLKQNYT 121
            .::...||..:..::....:|..||..:.........:.|.|:..:...|....|.:.|:...|
Zfish    70 ADKNCSKIHYISPNIYCCGAGTAADTEMTTQIISSNLELHSLSTGRLPRVATANRMLKQMLFRY- 133

  Fly   122 QSNGRRPFGLSCLVGGFDEDGTPHLFQTDPSGIFYEWRANTTGRSSQPVRDYMEKHADEILTIAD 186
                :...|.:.::||.|..| |||:...|.|...:....|.|..|.......|   |......:
Zfish   134 ----QGYIGAALVLGGVDCTG-PHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFE---DRYRPDME 190

  Fly   187 EAAAIKHIVRTLVSVSSLNH----TQMEVAVL 214
            |..| |.:||..::....|.    :.::|.|:
Zfish   191 EEDA-KSLVRDAIAAGIFNDLGSGSNIDVCVI 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha4T2	NP_001286844.1	arc_protsome_A	5..215	CDD:163366	49/227 (22%)
Prosalpha4T2	NP_001286844.1	Ntn_hydrolase	5..214	CDD:294319	48/225 (21%)
psmb7	XP_021324576.1	proteasome_beta_type_7	44..232	CDD:239732	40/188 (21%)
psmb7	XP_021324576.1	Pr_beta_C	237..280	CDD:315191
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810