DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha4T2 and PSMB10

DIOPT Version :9

Sequence 1:	NP_001286844.1	Gene:	Prosalpha4T2 / 37910	FlyBaseID:	FBgn0017556	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_002792.1	Gene:	PSMB10 / 5699	HGNCID:	9538	Length:	273	Species:	Homo sapiens

Alignment Length:	172	Identity:	40/172 - (23%)
Similarity:	73/172 - (42%)	Gaps:	12/172 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LQVEYAQEAVRRGSTVMGLRTNNAIVIGVEKRSVGD-LQEERMVRKICMLDDHVVMTFSGLTADA 82
            |:|.:|:   :.|:|:.||...:.:::|.:.|:..| :..::...||..:...:....:|:.|||
Human    30 LKVPHAR---KTGTTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADA 91

  Fly    83 RILVSRAQMEAQSHRLNFEKPTTVEYITRYIAQLKQNYTQSNGRRPFGLSCLVGGFDEDGTPHLF 147
            .:.......:.:.|.|:..:...|..:||.:.|....|     :...|.|.:|||.|..| |.|:
Human    92 EMTTRMVASKMELHALSTGREPRVATVTRILRQTLFRY-----QGHVGASLIVGGVDLTG-PQLY 150

  Fly   148 QTDPSGIFYEWRANTTGRSSQPVRDYMEKHADEILTIADEAA 189
            ...|.|.:........|.........:|......:|:  |||
Human   151 GVHPHGSYSRLPFTALGSGQDAALAVLEDRFQPNMTL--EAA 190

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha4T2	NP_001286844.1	arc_protsome_A	5..215	CDD:163366	40/172 (23%)
Prosalpha4T2	NP_001286844.1	Ntn_hydrolase	5..214	CDD:294319	40/172 (23%)
PSMB10	NP_002792.1	proteasome_beta_type_7	40..227	CDD:239732	36/159 (23%)
PSMB10	NP_002792.1	Pr_beta_C	232..267	CDD:403609
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810