DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha4T2 and PSMB5

DIOPT Version :9

Sequence 1:	NP_001286844.1	Gene:	Prosalpha4T2 / 37910	FlyBaseID:	FBgn0017556	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_002788.1	Gene:	PSMB5 / 5693	HGNCID:	9542	Length:	263	Species:	Homo sapiens

Alignment Length:	126	Identity:	24/126 - (19%)
Similarity:	58/126 - (46%)	Gaps:	10/126 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 GSTVMGLRTNNAIVIGVEKR-SVGDLQEERMVRKICMLDDHVVMTFSGLTADARILVSRAQMEAQ 94
            |:|.:..:..:.:::..:.| :.|.....:.|:|:..::.:::.|.:|..||..........:.:
Human    59 GTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCR 123

  Fly    95 SHRLNFEKPTTVEYITRYIAQLKQNYTQSNGRRPFGLS--CLVGGFDEDGTPHLFQTDPSG 153
            .:.|..::..:|...::.:|.:...|      :..|||  .::.|:|:.| |.|:..|..|
Human   124 IYELRNKERISVAAASKLLANMVYQY------KGMGLSMGTMICGWDKRG-PGLYYVDSEG 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha4T2	NP_001286844.1	arc_protsome_A	5..215	CDD:163366	24/126 (19%)
Prosalpha4T2	NP_001286844.1	Ntn_hydrolase	5..214	CDD:294319	24/126 (19%)
PSMB5	NP_002788.1	proteasome_beta_type_5	60..247	CDD:239730	23/125 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810