Protein Alignment Prosalpha4T2 and PSMA3

DIOPT Version :10

• Sequence 1: NP_611920.1
• Gene: Prosalpha4T2 / 37910
• FlyBaseID: FBgn0017556
• Length: 252
• Species: Drosophila melanogaster
• Sequence 2: NP_002779.1
• Gene: PSMA3 / 5684
• HGNCID: 9532
• Length: 255
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 75/254 - (29%)
• Similarity: 124/254 - (48%)
• Gaps: 24/254 - (9%)

  Fly     5 YDRAVTIYSPDGHLLQVEYAQEAVRRGSTVMGLRTNNAIVIGVEKRSVGDLQEERMVRKICMLDD 69
            ||.:.:.:||||.:.|||||.:||...||.:|:|..:.:|.||||..:..|.||...:::..:|.
Human     8 YDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRLFNVDR 72

  Fly    70 HVVMTFSGLTADARILVSRAQMEAQSHRLNFEKPTTVEYITRYIAQLKQNYTQSNGRRPFGLSCL 134
            ||.|..:||.||||.|...|:.||.:.|.||.....::::...:|.....||..:..||||.|.:
Human    73 HVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSAVRPFGCSFM 137

  Fly   135 VGGFDEDGTPHLFQTDPSGIFYEWRANTTGRSSQPVRDYMEKHADEILTIAD---EAAAIKHIVR 196
            :|.:..:....|:..||||:.|.:.....|::.|..:..:||...:.:|..|   |.|.|.:||.
Human   138 LGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMTCRDIVKEVAKIIYIVH 202

  Fly   197 TLVS----------VSSLNHTQMEVAVLKYRQPLRMIDHQVLADLERTVRREIEDEAEA 245
            ..|.          |..|.:.:.|:           :...:..:.|:..:..:::|.|:
Human   203 DEVKDKAFELELSWVGELTNGRHEI-----------VPKDIREEAEKYAKESLKEEDES 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha4T2	NP_611920.1	Ntn_hydrolase	5..214	CDD:469781	72/221 (33%)
PSMA3	NP_002779.1	proteasome_alpha_type_3	5..217	CDD:239720	69/208 (33%)