DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha4T2 and psmb10

DIOPT Version :9

Sequence 1:	NP_001286844.1	Gene:	Prosalpha4T2 / 37910	FlyBaseID:	FBgn0017556	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_001002543.2	Gene:	psmb10 / 436816	ZFINID:	ZDB-GENE-040718-278	Length:	276	Species:	Danio rerio

Alignment Length:	217	Identity:	52/217 - (23%)
Similarity:	88/217 - (40%)	Gaps:	29/217 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 AQEAVRRGSTVMGLRTNNAIVIGVEKRSVGDL-QEERMVRKICMLDDHVVMTFSGLTADARILVS 87
            |..|.:.|:|:.||...:.:::|.:.|:..|: ..::...||..:..::....:|:.|||.:...
Zfish    35 APNARKTGTTIAGLVFKDGVILGADTRATDDMVVADKNCMKIHYIAPNIYCCGAGVAADAEVTTQ 99

  Fly    88 RAQMEAQSHRLNFEKPTTVEYITRYIAQLKQNYTQSNGRRPFGLSCLVGGFDEDGTPHLFQTDPS 152
            ......:.|.|:..:|..|..:||   ||||...:..|.  .|.|.:|||.|.:|. .|:...|.
Zfish   100 MMSSNVELHSLSTGRPPLVAMVTR---QLKQMLFRYQGH--IGSSLIVGGVDVNGA-QLYSVYPH 158

  Fly   153 GIFYEWRANTTGRSSQPVRDYMEKHADEILTIAD------EAAAIKHIVRTLVS------VSSLN 205
            |.:.:....|.|..:          |..|....|      |....|.:||..::      :.|.:
Zfish   159 GSYDKLPFLTMGSGA----------ASAISVFEDRYKPNMELEEAKQLVRDAITAGIFCDLGSGS 213

  Fly   206 HTQMEVAVLKYRQPLRMIDHQV 227
            :..:.|...|....||..|..|
Zfish   214 NVDLCVITDKKVDYLRTYDQPV 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha4T2	NP_001286844.1	arc_protsome_A	5..215	CDD:163366	47/203 (23%)
Prosalpha4T2	NP_001286844.1	Ntn_hydrolase	5..214	CDD:294319	47/202 (23%)
psmb10	NP_001002543.2	PRE1	40..224	CDD:223711	45/199 (23%)
		proteasome_beta_type_7	43..231	CDD:239732	47/203 (23%)
		Pr_beta_C	237..270	CDD:289249
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900