DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha4T2 and pre6

DIOPT Version :9

Sequence 1:	NP_001286844.1	Gene:	Prosalpha4T2 / 37910	FlyBaseID:	FBgn0017556	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_595165.1	Gene:	pre6 / 2540175	PomBaseID:	SPBC106.16	Length:	259	Species:	Schizosaccharomyces pombe

Alignment Length:	247	Identity:	115/247 - (46%)
Similarity:	170/247 - (68%)	Gaps:	10/247 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 YDRAVTIYSPDGHLLQVEYAQEAVRRGSTVMGLRTNNAIVIGVEKRSVGDLQEERMVRKICMLDD 69
            ||||::::||||.||||||.|||||||:|.:.||.|..||||||:::|..||.....:||.|:|:
pombe     4 YDRALSVFSPDGRLLQVEYGQEAVRRGTTAIALRGNECIVIGVERKNVPKLQNVSNFQKIAMVDN 68

  Fly    70 HVVMTFSGLTADARILVSRAQMEAQSHRLNFEKPTTVEYITRYIAQLKQNYTQSNGRRPFGLSCL 134
            ||.:.|:||.||||||:.:|::|||:|:||...|.::||:|||:|.::|.||||.|.||||:|.|
pombe    69 HVCLAFAGLNADARILIDKARVEAQNHKLNLADPVSIEYLTRYVAGVQQKYTQSGGVRPFGVSTL 133

  Fly   135 VGGFD-EDGTPHLFQTDPSGIFYEWRANTTGRSSQPVRDYMEKHADEILTIADEAAAIKHIVRTL 198
            :.||| .|.||.::||:|:||:..|:|...||:|:..|:|:||:..|.|: .||  .|...|.:|
pombe   134 IAGFDVGDNTPRVYQTEPAGIYNAWKATAIGRASKAAREYLEKNWKEGLS-RDE--TIHLAVSSL 195

  Fly   199 VSVSSLNHTQMEVAVLKYRQPLRMIDHQVLADLERTVRREIED--EAEASRR 248
            :.|.......:|:|::...:.:..:.    :|...|:.:||:|  ||||:|:
pombe   196 LEVVQTASGNIELAIMDPGKDVEFLH----SDKIDTIVKEIQDEKEAEAARK 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha4T2	NP_001286844.1	arc_protsome_A	5..215	CDD:163366	105/210 (50%)
Prosalpha4T2	NP_001286844.1	Ntn_hydrolase	5..214	CDD:294319	105/209 (50%)
pre6	NP_595165.1	PRK03996	1..232	CDD:235192	107/234 (46%)
pre6	NP_595165.1	proteasome_alpha_type_7	4..211	CDD:239724	105/209 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	201	1.000	Domainoid score	I650
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	265	1.000	Inparanoid score	I730
OMA	1	1.010	-	-		QHG62217
OrthoFinder	1	1.000	-	-		FOG0002043
OrthoInspector	1	1.000	-	-		otm47071
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11599
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1345
TreeFam	1	0.960	-	-
	10	9.930