DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Prosalpha4T2 and Psmb7

DIOPT Version :9

Sequence 1:	NP_001286844.1	Gene:	Prosalpha4T2 / 37910	FlyBaseID:	FBgn0017556	Length:	252	Species:	Drosophila melanogaster
Sequence 2:	NP_035317.1	Gene:	Psmb7 / 19177	MGIID:	107637	Length:	277	Species:	Mus musculus

Alignment Length:	238	Identity:	51/238 - (21%)
Similarity:	96/238 - (40%)	Gaps:	35/238 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 AVTIYSPD-----------GHLLQVEYAQ------EAVRRGSTVMGLRTNNAIVIGVEKRSV-GD 54
            ||:::.|.           ..:|:.::|:      :|.:.|:|:.|:...:.||:|.:.|:. |.
Mouse     3 AVSVFQPPVGGFSFDNCRRNAVLEADFAKKGFKLPKARKTGTTIAGVVYKDGIVLGADTRATEGM 67

  Fly    55 LQEERMVRKICMLDDHVVMTFSGLTADARILVSRAQMEAQSHRLNFEKPTTVEYITRYIAQLKQN 119
            :..::...||..:..::....:|..||..:.........:.|.|...:...|....|.:.|:...
Mouse    68 VVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLISSNLELHSLTTGRLPRVVTANRMLKQMLFR 132

  Fly   120 YTQSNGRRPFGLSCLVGGFDEDGTPHLFQTDPSGIFYEWRANTTGRSS--------QPVRDYMEK 176
            |     :...|.:.::||.|..| |||:...|.|...:....|.|..|        ...|..||:
Mouse   133 Y-----QGYIGAALVLGGVDVTG-PHLYSIYPHGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEE 191

  Fly   177 HADEILTIADEAAAIKHIVRTLVSVSSLNHTQMEVAVLKYRQP 219
              :|...:..||.| ..|...|.|.|:::...:..:.|.:.:|
Mouse   192 --EEAKKLVSEAIA-AGIFNDLGSGSNIDLCVISKSKLDFLRP 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Prosalpha4T2	NP_001286844.1	arc_protsome_A	5..215	CDD:163366	49/232 (21%)
Prosalpha4T2	NP_001286844.1	Ntn_hydrolase	5..214	CDD:294319	49/231 (21%)
Psmb7	NP_035317.1	PRE1	41..225	CDD:223711	43/192 (22%)
		proteasome_beta_type_7	44..232	CDD:239732	44/197 (22%)
		Pr_beta_C	236..271	CDD:289249
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0638
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900