Sequence 1: | NP_002244.1 | Gene: | KDR / 3791 | HGNCID: | 6307 | Length: | 1356 | Species: | Homo sapiens |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_524394.2 | Gene: | htl / 42160 | FlyBaseID: | FBgn0010389 | Length: | 729 | Species: | Drosophila melanogaster |
Alignment Length: | 844 | Identity: | 233/844 - (27%) |
---|---|---|---|
Similarity: | 347/844 - (41%) | Gaps: | 219/844 - (25%) |
- Green bases have known domain annotations that are detailed below.
Human 458 WYWQLEEECANEPSQA-------VSVTNPYPCEEWRSVEDFQGGNKIEVNKNQFALIEGKNKTVS 515
Human 516 TLVIQAANVSALYKCEA--------VNKVG-----------RGERVISFHVTR--GPEITLQPDM 559
Human 560 QPTEQESVSLWCTADRSTFENLTWYKLGPQPLPIHVGELPTPVCKNLDTLWKLNATMFSNSTNDI 624
Human 625 LIMELKNASLQDQGDYVCLAQDRKTKKRHCVVRQLTVLERV--APTI-TGNLENQTTSIGESIEV 686
Human 687 SCTASGNPPPQIMWF----------KDNETLVEDSGIVLKDGNRNLTIRRVRKEDEGLYTCQACS 741
Human 742 VLGCAKVEAFF------------IIEGAQEKTNLEIIILVGTAVIAMFFWLLLVIILRTVK---- 790
Human 791 ------------------RANGGELKTGYLSIVMDP----------------DELPLDEHCERLP 821
Human 822 YDASKWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKTATCRTVAVKMLKEGATHSEHRALMSEL 886
Human 887 KILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFVPYKTKGARFRQGKDY 951
Human 952 VGAIPVDLKRRLDSITSSQSSASSGFVEEKSLSDVEEEEAPEDLYKDFLTLEHLICYSFQVAKGM 1016
Human 1017 EFLASRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRKG-DARLPLKWMAPETIFDR 1080
Human 1081 VYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHG 1145
Human 1146 EPSQRPTFSELVEHLGNLLQANAQQDGKDYIVLPISETLSMEEDSGLSLPTSPVSCMEEEEVCD 1209 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
KDR | NP_002244.1 | Ig | 41..109 | CDD:299845 | |
IG_like | 231..324 | CDD:214653 | |||
Ig1_VEGFR | 239..326 | CDD:143270 | |||
IG_like | 340..417 | CDD:214653 | |||
Ig2_VEGFR-2 | 348..417 | CDD:143272 | |||
Ig_2 | 551..661 | CDD:290606 | 20/109 (18%) | ||
IG | 565..661 | CDD:214652 | 18/95 (19%) | ||
I-set | 667..754 | CDD:254352 | 23/109 (21%) | ||
IGc2 | 680..744 | CDD:197706 | 14/73 (19%) | ||
PTKc_VEGFR2 | 826..1167 | CDD:270681 | 136/341 (40%) | ||
Pkinase_Tyr | 834..1160 | CDD:285015 | 129/326 (40%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1274..1318 | ||||
htl | NP_524394.2 | Ig | 112..191 | CDD:299845 | 23/116 (20%) |
IG_like | 113..191 | CDD:214653 | 23/115 (20%) | ||
IG_like | 205..289 | CDD:214653 | 20/91 (22%) | ||
PKc_like | 404..692 | CDD:304357 | 136/343 (40%) | ||
STYKc | 416..688 | CDD:214568 | 129/326 (40%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG0200 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |