| Sequence 1: | NP_002244.1 | Gene: | KDR / 3791 | HGNCID: | 6307 | Length: | 1356 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_608762.3 | Gene: | CG3277 / 33543 | FlyBaseID: | FBgn0031518 | Length: | 789 | Species: | Drosophila melanogaster |
| Alignment Length: | 870 | Identity: | 228/870 - (26%) |
|---|---|---|---|
| Similarity: | 364/870 - (41%) | Gaps: | 204/870 - (23%) |
- Green bases have known domain annotations that are detailed below.
|
Human 401 TNPI------SKEKQSHVVSLVVYVPPQIGEKSLISPVDSYQYG-------TTQTLTCTVYAIPP 452
Human 453 PH-HIHWYWQLEEECANEPSQAVSVTN-----PYPCEEWRSVEDFQGGNKIEVNKNQFALIEGKN 511
Human 512 KTVS-TLVIQAANVSALYKC------EAVN-KVGRGERVISFHVTRGPEITLQPDMQPTEQESVS 568
Human 569 LWCTADRSTFENLTWYKLGPQPLPIHVGELPTPVCKNLDTLWKLNATMFSNSTNDILIMELKNAS 633
Human 634 LQDQGDYVCLAQDRKTKKRHCVVRQLTVLERVAPTIT--GNLENQTTSIGESIEVSCTASGNPPP 696
Human 697 QIMWFKDNETLVEDSGIVLKDGNRNLTIRRVRKEDEGLYTCQACSV--LGCAKVEAFFIIEGAQE 759
Human 760 KTNLEI----------------IILVGTAVIAMFFWLLLVIILRTVKRANGGELKTG---YL--- 802
Human 803 ---SIVMDPDELPLDEHCERLPY--DASKWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKTATC 862
Human 863 RTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACT-KPGGPLMVIVEFCKFGNLST 926
Human 927 YLRSKRNEFVPYKTKGARFRQGKDYVGAIPVDLKRRLDSITSSQSSASSGFVEEKSLS---DVEE 988
Human 989 EEA-----------------------PEDLYKDFLTLEHLICYSFQVAKGMEFLASRKCIHRDLA 1030
Human 1031 ARNILLSEKNVVKICDFGLARDIYKDPDYVRKGDARLPLKWMAPETIFDRVYTIQSDVWSFGVLL 1095
Human 1096 WEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHL 1160
Human 1161 G---NLLQANAQQDGKDYIVLPISE 1182 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| KDR | NP_002244.1 | Ig | 41..109 | CDD:299845 | |
| IG_like | 231..324 | CDD:214653 | |||
| Ig1_VEGFR | 239..326 | CDD:143270 | |||
| IG_like | 340..417 | CDD:214653 | 6/21 (29%) | ||
| Ig2_VEGFR-2 | 348..417 | CDD:143272 | 6/21 (29%) | ||
| Ig_2 | 551..661 | CDD:290606 | 19/109 (17%) | ||
| IG | 565..661 | CDD:214652 | 16/95 (17%) | ||
| I-set | 667..754 | CDD:254352 | 16/90 (18%) | ||
| IGc2 | 680..744 | CDD:197706 | 10/65 (15%) | ||
| PTKc_VEGFR2 | 826..1167 | CDD:270681 | 130/370 (35%) | ||
| Pkinase_Tyr | 834..1160 | CDD:285015 | 127/352 (36%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1274..1318 | ||||
| CG3277 | NP_608762.3 | STYKc | 426..763 | CDD:214568 | 127/352 (36%) |
| PTKc | 430..763 | CDD:270623 | 126/348 (36%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG0200 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||