Protein Alignment CG13579 and TAAR2

DIOPT Version :10

• Sequence 1: NP_001261169.1
• Gene: CG13579 / 37905
• FlyBaseID: FBgn0035010
• Length: 716
• Species: Drosophila melanogaster
• Sequence 2: NP_001028252.1
• Gene: TAAR2 / 9287
• HGNCID: 4514
• Length: 351
• Species: Homo sapiens
• Alignment Length: 450
• Identity: 89/450 - (19%)
• Similarity: 143/450 - (31%)
• Gaps: 172/450 - (38%)

  Fly    16 NSSCSHPRYSGHNFIAHIGIAETIEAVLILVLTLGVIGANCLVIFVINNRRYAAYIHQQPRYLLT 80
            |.||.....|       :|:...:.:.:...:.:.:.|...::|.:    .|...:|....:|:.
Human    30 NRSCPENERS-------LGVRVAMYSFMAGSIFITIFGNLAMIISI----SYFKQLHTPTNFLIL 83

  Fly    81 SLALNDLTIGLLITPFGLMPALFHCWPYGEIFCQIQALLRGALSQQSAVILVCMAVDRYMCALHP 145
            |:|:.|..:|..|.|:.::.::.:||.:|..||:|.......||..|...|..:|:||:....:|
Human    84 SMAITDFLLGFTIMPYSMIRSVENCWYFGLTFCKIYYSFDLMLSITSIFHLCSVAIDRFYAICYP 148

  Fly   146 RRYYQHSSKKGCVAILSLTWII-SLTVFGFLVLPKGYYFNNTG---LMACEPFYSKPSYRILSTC 206
            ..|....:......:|.|.|.: ....|| :|..:.|.....|   |:||.           |:|
Human   149 LLYSTKITIPVIKRLLLLCWSVPGAFAFG-VVFSEAYADGIEGYDILVACS-----------SSC 201

  Fly   207 ALYF----PTTM----------VLMYCYGSSFHMSRFRLNDPTMPLTAAAHHPHPHPHPTAAQQL 257
            .:.|    .||:          :::..||..|.:||                  .|.|  |...|
Human   202 PVMFNKLWGTTLFMAGFFTPGSMMVGIYGKIFAVSR------------------KHAH--AINNL 246

  Fly   258 QMHQHQQHHQQAGMHSHLYHGHSHHPSHPSHPNHPNHHGHPHHHGPPVMGHLSMAMSMGLAGMPN 322
            :.:|:.|
Human   247 RENQNNQ---------------------------------------------------------- 253

  Fly   323 MTNKITKKIVPIQEKNSSGSTSRSMAAISLGFI--VMVTPW-----TIQEIVTACTGSKLPPFLD 380
              .|..||                 ||.:||.:  |.:..|     ||          .|.|||:
Human   254 --VKKDKK-----------------AAKTLGIVIGVFLLCWFPCFFTI----------LLDPFLN 289

  Fly   381 F--------LVTWTALSNSLWNPFMYWLLNSDFRRMSRQLMPNKCFPHEDTPEHKSGCCH 432
            |        .:||....||..||.:|......|||..:.::..|.|         |.|.|
Human   290 FSTPVVLFDALTWFGYFNSTCNPLIYGFFYPWFRRALKYILLGKIF---------SSCFH 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13579	NP_001261169.1	7tm_classA_rhodopsin-like	41..>220	CDD:410626	42/196 (21%)
		TM helix 1	41..65	CDD:410626	2/23 (9%)
		TM helix 2	75..101	CDD:410626	7/25 (28%)
		TM helix 3	113..143	CDD:410626	9/29 (31%)
		TM helix 4	156..175	CDD:410626	5/19 (26%)
		TM helix 5	200..220	CDD:410626	5/33 (15%)
		7tm_GPCRs	<334..407	CDD:475119	21/87 (24%)
		TM helix 6	340..366	CDD:410628	8/32 (25%)
		TM helix 7	377..402	CDD:410628	11/32 (34%)
TAAR2	NP_001028252.1	7tmA_TAAR2_3_4	44..326	CDD:320437	79/404 (20%)
		TM helix 1	45..71	CDD:320437	2/29 (7%)
		TM helix 2	78..104	CDD:320437	7/25 (28%)
		TM helix 3	116..146	CDD:320437	9/29 (31%)
		TM helix 4	158..181	CDD:320437	6/23 (26%)
		TM helix 5	206..235	CDD:320437	5/28 (18%)
		TM helix 6	255..285	CDD:320437	11/56 (20%)
		TM helix 7	294..319	CDD:320437	7/24 (29%)